Department of Orthopaedic Surgery, The Affiliated Drum Tower Hospital of Nanjing University Medical School, Nanjing, China.
Orthop Surg. 2010 Nov;2(4):285-90. doi: 10.1111/j.1757-7861.2010.00101.x.
To evaluate the effectiveness and to identify the predictive factors of standardized brace treatment for girls with adolescent idiopathic scoliosis (AIS).
From July 2003 to July 2009, 142 girls with AIS completed standardized brace treatment. These patients had a mean age of (13.1 ± 1.5) years (range, 10.1-15.9 years), a mean main curve of 29.6°± 5.4° (range, 20°-40°), and a mean Risser grade of 2.0 ± 1.5 (range, 0-4) before brace treatment. Based on whether their scoliosis progressed or not, patients were divided into two groups: progressed (Group Pr, n = 27, 19%) and non-progressed (Group NP, n = 115, 81%), and were then divided into a further two groups: surgery (Group Su, n = 18, 13%) and non-surgery (Group NS, n = 124, 87%). χ(2) and logistic regression analyses were performed to investigate factors predicting outcomes of brace treatment.
The duration of brace treatment in all patients averaged 2.5 ± 1.0 years (range, 0.6-5.9). χ(2) analysis revealed that patients with progressive curves tended to be younger, with lower Risser grade, initial larger curve magnitude and a main thoracic curve pattern. Using stepwise logistic regression, pre-menarche status (P= 0.00028) and a main thoracic curve pattern (P= 0.012) were found to be independent risk factors of curve progression despite brace treatment, while an initial Cobb angle >30° (P= 0.022) was an additional independent risk factor of curve requiring surgery due to progression.
Brace treatment can prevent curve progression in most girls with AIS. The outcomes of brace treatment in these girls are influenced by growth status, curve pattern and curve magnitude. Less mature patients, and those with larger curves and thoracic curves are at risk of scoliosis progression despite brace treatment.
评估标准化支具治疗对青少年特发性脊柱侧凸(AIS)女孩的疗效,并确定其预测因素。
2003 年 7 月至 2009 年 7 月,142 例 AIS 女孩完成了标准化支具治疗。这些患者的平均年龄为(13.1±1.5)岁(范围,10.1-15.9 岁),主弯平均度数为 29.6°±5.4°(范围,20°-40°),支具治疗前 Risser 征平均为 2.0±1.5(范围,0-4)。根据脊柱侧凸是否进展,将患者分为进展组(Pr 组,n=27,19%)和未进展组(NP 组,n=115,81%),进一步分为手术组(Su 组,n=18,13%)和非手术组(NS 组,n=124,87%)。采用卡方检验和 logistic 回归分析探讨预测支具治疗效果的因素。
所有患者支具治疗的平均时间为 2.5±1.0 年(范围,0.6-5.9 年)。卡方检验显示,进展组患者的年龄较小,Risser 征较低,初始曲度较大,主弯类型为胸弯。采用逐步 logistic 回归分析,发现初潮前状态(P=0.00028)和主胸弯类型(P=0.012)是支具治疗后脊柱侧凸进展的独立危险因素,而初始 Cobb 角>30°(P=0.022)是由于进展需要手术的附加独立危险因素。
支具治疗可预防大多数 AIS 女孩的脊柱侧凸进展。这些女孩支具治疗的效果受生长状态、曲线类型和曲线幅度的影响。尽管接受了支具治疗,发育不成熟的患者、曲度较大的患者和胸弯患者发生脊柱侧凸进展的风险更高。