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西澳大利亚州原住民和非原住民中2009年甲型H1N1流感大流行引发的慢性病与住院情况

Chronic disease and hospitalisation for pandemic (H1N1) 2009 influenza in Indigenous and non-Indigenous Western Australians.

作者信息

Goggin Leigh S, Carcione Dale, Mak Donna B, Dowse Gary K, Giele Carolien M, Smith David W, Effler Paul V

机构信息

Department of Health Western Australia, Perth, Western Australia.

出版信息

Commun Dis Intell Q Rep. 2011 Jun;35(2):172-6.

Abstract

Indigenous and non-indigenous Western Australians with pandemic (H1N1) 2009 influenza (pH1N1) infection were compared for risk factors, influenza vaccination history, symptoms, use of antiviral medications, and hospitalisation. Data were collected systematically on 856 notified cases with laboratory confirmed pH1N1 infection during the first 10 weeks of pH1N1 virus transmission in Western Australia in 2009. Indigenous people with pH1N1 were approximately 3 times more likely to be hospitalised and were more likely to have a range of underlying medical conditions and be smokers, compared with non-Indigenous cases. Age (P < 0.001) and the presence of two or more co-morbidities (P < 0.001) were independent predictors of hospitalisation, while Indigenous status was not, indicating that higher pH1N1 hospitalisation rates in Indigenous Australians during the 2009 winter season were attributable to the higher prevalence of underlying chronic disease. These results underscore the need to ensure that influenza vaccination is delivered as widely as possible among those with chronic health conditions.

摘要

对感染2009年大流行性甲型流感(H1N1)(pH1N1)的西澳大利亚原住民和非原住民的危险因素、流感疫苗接种史、症状、抗病毒药物使用情况及住院情况进行了比较。2009年西澳大利亚pH1N1病毒传播的前10周,对856例实验室确诊的pH1N1感染病例进行了系统的数据收集。与非原住民病例相比,感染pH1N1的原住民住院可能性约高3倍,且更有可能患有一系列基础疾病且为吸烟者。年龄(P < 0.001)和存在两种或更多合并症(P < 0.001)是住院的独立预测因素,而原住民身份则不是,这表明2009年冬季澳大利亚原住民中较高的pH1N1住院率归因于基础慢性病的较高患病率。这些结果强调了确保在患有慢性健康状况的人群中尽可能广泛地接种流感疫苗的必要性。

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