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应用组织多普勒光相干断层成像技术对活体鸡胚心脏的应变和应变速率进行评估。

Assessment of strain and strain rate in embryonic chick heart in vivo using tissue Doppler optical coherence tomography.

机构信息

Department of Bioengineering, University of Washington, Seattle, WA 98195, USA.

出版信息

Phys Med Biol. 2011 Nov 21;56(22):7081-92. doi: 10.1088/0031-9155/56/22/006. Epub 2011 Oct 21.

Abstract

We present a method to assess the in vivo radial strain and strain rate of the myocardial wall, which is of great importance to understand the biomechanics of cardiac development, using tissue Doppler optical coherence tomography (tissue-DOCT). Combining the structure and velocity information acquired from tissue-DOCT, the velocity distribution in the myocardial wall is plotted, from which the radial strain and strain rate are evaluated. The results demonstrate that tissue-DOCT can be used as a useful tool to describe tissue deformation, especially, the biomechanical characteristics of the embryonic heart.

摘要

我们提出了一种利用组织多普勒光学相干断层扫描(tissue-DOCT)评估心肌壁体内径向应变和应变速率的方法。该方法结合组织 DOCT 获得的结构和速度信息,绘制心肌壁内的速度分布,从而评估径向应变和应变速率。结果表明,组织 DOCT 可作为描述组织变形的有用工具,特别是胚胎心脏的生物力学特征。

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