Department of Dermatology and Allergy, University of Bonn, Sigmund-Freud Str. 25, D-53105 Bonn, Germany.
Curr Opin Immunol. 2011 Dec;23(6):778-83. doi: 10.1016/j.coi.2011.09.007. Epub 2011 Oct 19.
Atopic dermatitis (AD) results from barrier defects combined with modified immune responses of the innate and the adaptive immune system to exogenous and endogenous factors. Recent research has continued to sort out the complex pathophysiologic puzzle of this frequent skin disease. However, the network of mechanisms leading to the manifestation of AD is far from being completely understood.
特应性皮炎(AD)是由屏障缺陷与先天和适应性免疫系统对外源性和内源性因素的改变免疫反应共同导致的。最近的研究继续梳理这种常见皮肤病复杂的病理生理难题。然而,导致 AD 表现的机制网络还远未被完全理解。