The Department of Obstetrics and Gynecology, Faculty of Medicine, Menofyia University, Egypt.
Eur J Obstet Gynecol Reprod Biol. 2012 Jan;160(1):18-21. doi: 10.1016/j.ejogrb.2011.09.035. Epub 2011 Oct 22.
To determine whether abdominal electromyography can predict the response to tocolysis in pregnant women in preterm labor.
This study was carried out at the Department of Obstetrics and Gynecology, Menofyia University Hospital in Egypt. Fifty pregnant women in preterm labor who fulfilled the inclusion criteria were enrolled. Baseline abdominal electromyography was performed. Tocolysis in the form of hexoprenaline sulphate infusion was started for all women and electromyography was repeated after 24h in responders but only after 6h in non responders. The receiver operating characteristics curve was drawn to calculate specificity of the electromyography at 100% sensitivity. Results were tabulated and statistically analyzed.
Forty women responded to tocolysis by delaying delivery for more than 48 h. There was a significant reduction in the frequency of uterine contractions after tocolysis (3.76 ± 0.92 versus 2.32 ± 2.05 contractions per 10 min; P<0.001). Similar significant reductions affected the duration and amplitude of uterine action potentials (25.08 ± 9.74 versus 14.4 ± 17.16s; P<0.001, 40.8 ± 25.89 versus 28.32 ± 29.38 mV; P<0.001). At a sensitivity of 100% and using ROC curve, abdominal electromyography of amplitude of 82 mV lasting for 30s or more had a specificity of 90%, positive and negative predictive values of 67% and 95%, and a diagnostic accuracy of 88% in predicting preterm labor.
Abdominal electromyography may predict the response to tocolysis in preterm labor.
确定腹部肌电图能否预测早产孕妇保胎治疗的反应。
本研究在埃及曼菲利亚大学医院妇产科进行。纳入了 50 名符合纳入标准的早产孕妇。对所有孕妇进行基线腹部肌电图检查。所有孕妇均给予硫酸己丙肾上腺素保胎治疗，并在应答者中 24 小时后、无应答者中 6 小时后重复肌电图检查。绘制受试者工作特征曲线，计算肌电图在 100%灵敏度下的特异性。结果进行制表和统计学分析。
40 名孕妇通过保胎治疗使分娩时间延长超过 48 小时。保胎治疗后子宫收缩频率明显降低（3.76±0.92 次/10 分钟比 2.32±2.05 次/10 分钟；P<0.001）。子宫动作电位的持续时间和幅度也出现类似的显著降低（25.08±9.74 秒比 14.4±17.16 秒；P<0.001，40.8±25.89 mV 比 28.32±29.38 mV；P<0.001）。当灵敏度为 100%且使用 ROC 曲线时，振幅为 82 mV、持续时间超过 30 秒的腹部肌电图预测早产的特异性为 90%，阳性预测值、阴性预测值和诊断准确率分别为 67%、95%和 88%。
腹部肌电图可能预测早产保胎治疗的反应。
