Gregory D L, Jones C D, Denton E R E, Harnett A N
Department of Oncology, Addenbrookes Hospital, Cambridge, UK.
Clin Med Oncol. 2008;2:37-42. doi: 10.4137/cmo.s339. Epub 2008 Feb 9.
We present a case of a female patient who developed acute onset of visual loss due to central serous retinopathy as a consequence of steroid premedication for docetaxol given as second line neoadjuvant chemotherapy for breast cancer. Central serous retinopathy is a recognised association with steroids but has not been previously reported in association with the management of solid tumours. Reduction in steroid dose and duration permitted recovery of her visual acuity while allowing completion of the prescribed chemotherapy regimen. An overview of the presentation, pathogenesis, aetiologies and management of central serous retinopathy is given.
我们报告了一例女性患者，该患者因在多西他赛二线新辅助化疗治疗乳腺癌中行类固醇预处理后发生中心性浆液性视网膜病变，导致急性视力丧失。中心性浆液性视网膜病变与类固醇的关联已得到公认，但此前尚未有与实体瘤治疗相关的报道。降低类固醇剂量和缩短使用时间使她的视力得以恢复，同时也能完成规定的化疗方案。本文对中心性浆液性视网膜病变的临床表现、发病机制、病因及治疗进行了概述。
