Kurttio P, Kalliokoski P, Lampelo S, Jantunen M J
University of Kuopio, Department of Environmental Sciences, Finland.
Mutat Res. 1990 Sep;242(1):9-15. doi: 10.1016/0165-1218(90)90094-i.
The mutagenicity of fumes from the heating of freshly cut spruce and birch chips was measured with Salmonella typhimurium strains TA98, TA100 and TA102. The bacteria were exposed directly and indirectly to the fumes. Wood chips were also extracted with solvents. No mutagenicity was found in wood extracts or the fume samples measured indirectly. The results from the direct exposure experiments indicate, however, that drying spruce and birch at 170 degrees C emits mutagenic compounds, which are short-lived and/or volatile. One of the mutagenic compounds of the fumes is probably 3-carene. These results are consistent with previous epidemiological findings, which suggest that these fumes are carcinogenic.
利用鼠伤寒沙门氏菌TA98、TA100和TA102菌株测定了新鲜切割的云杉和桦木片加热产生的烟雾的致突变性。细菌直接和间接暴露于烟雾中。木片也用溶剂进行了提取。在木材提取物或间接测量的烟雾样品中未发现致突变性。然而，直接暴露实验的结果表明，在170摄氏度下干燥云杉和桦木会释放出致突变化合物，这些化合物寿命短和/或具有挥发性。烟雾中的一种致突变化合物可能是3-蒈烯。这些结果与先前的流行病学研究结果一致，表明这些烟雾具有致癌性。
