用于血管内共配准成像的集成超声和光声探头。
Integrated ultrasound and photoacoustic probe for co-registered intravascular imaging.
机构信息
Wuhan University, Department of Physics and Key Laboratory of Acoustic and Photonic Materials and Devices, Ministry of Education, Wuhan 430072, China.
出版信息
J Biomed Opt. 2011 Oct;16(10):106001. doi: 10.1117/1.3631798.
Abstract
We report on the synergy of an integrated ultrasound (US) and photoacoustic (PA) probe system for intravascular imaging. The combined dual-modality probe is based on a 39 MHz ring-shaped US transducer which detects both US echoes and laser-generated PA signals. By combining optical fiber, US transducer, and micromirror, we can obtain intravascular cross-sectional B-scan images by internal illumination of the sample. The performance of the probe is evaluated in a phantom study. Moreover, the coaxially designed probe also provides co-registered US and PA images of a normal rabbit aorta, which demonstrates the imaging ability of the dual-functional system, implying future clinical applications.
摘要
我们报告了一种用于血管内成像的集成超声（US）和光声（PA）探头系统的协同作用。该组合式双模态探头基于 39MHz 的环形 US 换能器，可检测 US 回波和激光产生的 PA 信号。通过将光纤、US 换能器和微镜结合在一起，我们可以通过对样品进行内部照明来获得血管内横截面 B 扫描图像。在体模研究中评估了探头的性能。此外，同轴设计的探头还提供了正常兔主动脉的 US 和 PA 共定位图像，这证明了该双功能系统的成像能力，预示着未来的临床应用。
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