Department of Radiology, Weill Cornell Imaging at New York Presbyterian Hospital, New York, New York, USA.
J Magn Reson Imaging. 2012 Mar;35(3):711-6. doi: 10.1002/jmri.22853. Epub 2011 Oct 26.
To compare image quality including the number of perforators visualized, vessel contrast ratios, and vessel sharpness with blood pool and extracellular contrast agents in abdominal perforator flap magnetic resonance angiography (MRA).
Preoperative perforator flap MRA was performed prone on 64 consecutive patients undergoing breast reconstruction (32 receiving 20 mL gadobenate dimeglumine and 32 receiving 10 mL gadofosveset trisodium) on transverse 3D fat-suppressed spoiled gradient echo images using high spatial resolution. Image quality was assessed qualitatively on a 4-point scale. On a computer workstation the number of perforators visualized was counted, arterial, venous, muscle, fat, and abdominal perforator signal intensities were measured to calculate signal intensity and contrast ratios, and vessel sharpness was evaluated.
The qualitative image quality score was higher for gadofosveset (2.7) than gadobenate (2.0) and CTA (2.0). The mean number of perforators visualized with gadofosveset was 6.8 on right and 10.4 on left compared to 4.6 on right and 6.6 on left for gadobenate (P < 0.0001). The artery-to-fat contrast ratio was comparable, suggesting the difference was not related to magnitude of enhancement. Perforator-to-muscle contrast ratio was greater for gadofosveset, 2.3, compared to gadobenate 1.5 (P = 0.002). Vessel sharpness was also greater for gadofosveset (P = 0.006).
Perforator MRA image quality including number of perforators visualized, perforator-to-muscle contrast, and vessel sharpness is higher with gadofosveset trisodium compared with gadobenate dimeglumine.
比较腹部穿支皮瓣磁共振血管造影（MRA）中血池和细胞外对比剂的成像质量，包括可视化穿支数量、血管对比率和血管锐利度。
对 64 例接受乳房重建术的患者（32 例接受 20 毫升钆贝葡胺，32 例接受 10 毫升钆佛醇三钠）行术前俯卧位 MRA，采用高空间分辨率横向 3D 脂肪抑制扰相梯度回波序列，使用血池和细胞外对比剂。使用 4 分制对图像质量进行定性评估。在计算机工作站上，计算可视化穿支的数量，测量动脉、静脉、肌肉、脂肪和腹部穿支的信号强度，以计算信号强度和对比率，并评估血管锐利度。
与钆贝葡胺（2.0）和 CTA（2.0）相比，钆佛醇的图像质量评分更高（2.7）。右、左侧钆佛醇可见穿支数量分别为 6.8 和 10.4，而右、左侧钆贝葡胺分别为 4.6 和 6.6（P<0.0001）。动脉-脂肪对比率相似，提示增强幅度差异与增强效果无关。与钆贝葡胺（1.5）相比，钆佛醇的穿支-肌肉对比率更高（2.3，P=0.002）。血管锐利度也更高（P=0.006）。
与钆贝葡胺相比，使用钆佛醇三钠进行腹部穿支皮瓣 MRA 可提高成像质量，包括可视化穿支数量、穿支-肌肉对比和血管锐利度。
