正常胎儿的环向和纵向心室应变。
Circumferential and longitudinal ventricular strain in the normal human fetus.
机构信息
Department of Cardiology, Children's Hospital Boston, and Harvard Medical School, Boston, Massachusetts 02115, USA.
出版信息
J Am Soc Echocardiogr. 2012 Jan;25(1):105-11. doi: 10.1016/j.echo.2011.09.016. Epub 2011 Oct 26.
Abstract
BACKGROUND
Echocardiography with speckle tracking is a novel, angle-independent technique for assessing global and regional cardiac function. Normal data on longitudinal strain have been reported for human fetuses. The aim of this study was to define circumferential left ventricular (LV) strain in a normal fetal population.
METHODS
Singleton fetuses between 17 and 42 weeks in gestational age with no adverse maternal health issues or fetal abnormalities were studied. Regional and averaged cardiac strain were measured using syngo Velocity Vector Imaging software.
RESULTS
Data from 81 fetuses were analyzed (mean gestational age, 29.2 ± 5.7 weeks). Overall, average midventricular circumferential strain was 18.7 ± 3.3%, LV longitudinal strain was 15.2 ± 2.7%, and right ventricular longitudinal strain was 16.0 ± 3.3%, with no correlation with gestational age.
CONCLUSION
This is the first study to report normal fetal LV circumferential strain. These data may be useful as a reference for assessing fetal cardiac function. The retrospective study design and relatively low frame rates used in this study were important limitations.
摘要
背景
超声心动图斑点追踪技术是一种新颖的、与角度无关的评估整体和局部心脏功能的方法。已有关于人胎儿纵向应变的正常数据的报道。本研究旨在定义正常胎儿人群中的左心室（LV）圆周应变。
方法
研究了 81 例胎龄在 17 周至 42 周之间、无不良母婴健康问题或胎儿异常的单胎胎儿。使用 syngo Velocity Vector Imaging 软件测量局部和平均心脏应变。
结果
分析了 81 例胎儿的数据（平均孕龄为 29.2±5.7 周）。总体而言，平均心室中部圆周应变 18.7±3.3%，LV 纵向应变 15.2±2.7%，右心室纵向应变 16.0±3.3%，与孕龄无相关性。
结论
这是第一项报告正常胎儿 LV 圆周应变的研究。这些数据可能有助于评估胎儿心脏功能。本研究采用回顾性研究设计，帧频相对较低，这是重要的局限性。
相似文献
1
Circumferential and longitudinal ventricular strain in the normal human fetus.正常胎儿的环向和纵向心室应变。
J Am Soc Echocardiogr. 2012 Jan;25(1):105-11. doi: 10.1016/j.echo.2011.09.016. Epub 2011 Oct 26.
2
Left Ventricular Longitudinal and Circumferential Layer-Specific Myocardial Strains and Their Determinants in Healthy Subjects.健康受试者左心室纵向和圆周层面特异性心肌应变及其决定因素
Echocardiography. 2016 Apr;33(4):510-8. doi: 10.1111/echo.13132. Epub 2015 Dec 12.
3
Reference Ranges of Left Ventricular Strain Measures by Two-Dimensional Speckle-Tracking Echocardiography in Children: A Systematic Review and Meta-Analysis.二维斑点追踪超声心动图测量儿童左心室应变的参考范围：一项系统评价和荟萃分析
J Am Soc Echocardiogr. 2016 Mar;29(3):209-225.e6. doi: 10.1016/j.echo.2015.11.016. Epub 2015 Dec 30.
4
Fetal and Neonatal Diastolic Myocardial Strain Rate: Normal Reference Ranges and Reproducibility in a Prospective, Longitudinal Cohort of Pregnancies.胎儿及新生儿舒张期心肌应变率：前瞻性纵向妊娠队列中的正常参考范围及可重复性
J Am Soc Echocardiogr. 2016 Jul;29(7):663-9. doi: 10.1016/j.echo.2016.02.017. Epub 2016 Apr 1.
5
Age-related normal range of left ventricular strain and torsion using three-dimensional speckle-tracking echocardiography.应用三维斑点追踪技术评估左心室应变和扭转的年龄相关正常值。
J Am Soc Echocardiogr. 2014 Jan;27(1):55-64. doi: 10.1016/j.echo.2013.10.002. Epub 2013 Nov 13.
6
Longitudinal Changes and Interobserver Variability of Systolic Myocardial Deformation Values in a Prospective Cohort of Healthy Fetuses across Gestation and after Delivery.健康胎儿前瞻性队列中，孕期及产后收缩期心肌形变值的纵向变化及观察者间差异
J Am Soc Echocardiogr. 2016 Apr;29(4):341-9. doi: 10.1016/j.echo.2015.12.003. Epub 2016 Jan 12.
7
Left Ventricular Rotational and Twist Mechanics in the Human Fetal Heart.人胎儿心脏左心室旋转和扭转力学。
J Am Soc Echocardiogr. 2017 Aug;30(8):773-780.e1. doi: 10.1016/j.echo.2017.04.006. Epub 2017 Jun 7.
8
Pediatric Reference Values and Z Score Equations for Left Ventricular Systolic Strain Measured by Two-Dimensional Speckle-Tracking Echocardiography.二维斑点追踪超声心动图测量左心室收缩期应变的儿科参考值和Z评分方程
J Am Soc Echocardiogr. 2016 Aug;29(8):786-793.e8. doi: 10.1016/j.echo.2016.03.018. Epub 2016 May 13.
9
The use of strain, strain rate, and displacement by 2D speckle tracking for assessment of systolic left ventricular function in goats: applicability and influence of general anesthesia.二维斑点追踪技术利用应变、应变率和位移评估山羊左心室收缩功能：全身麻醉的适用性及影响
Cardiovasc Ultrasound. 2015 Mar 17;13:11. doi: 10.1186/s12947-015-0005-8.
10
Left ventricular three-dimensional global systolic strain by real-time three-dimensional speckle-tracking in children: feasibility, reproducibility, maturational changes, and normal ranges.实时三维斑点追踪技术测量儿童左心室整体三维收缩期应变：可行性、可重复性、发育变化及正常范围。
J Am Soc Echocardiogr. 2013 Aug;26(8):853-9. doi: 10.1016/j.echo.2013.05.002. Epub 2013 Jun 19.
引用本文的文献
1
Left and Right Ventricular Strain Mechanics in Fetal Tachyarrhythmia.胎儿快速心律失常时的左右心室应变力学
Fetal Diagn Ther. 2025 Jun 18:1-11. doi: 10.1159/000546991.
2
Evaluating the Impact of Maternal Lipid Profiles on Fetal Cardiac Function at Mid-Gestation: An Observational Study.评估孕中期母体血脂水平对胎儿心脏功能的影响：一项观察性研究。
Clin Pract. 2024 Nov 27;14(6):2590-2600. doi: 10.3390/clinpract14060204.
3
Normal values and distribution of ventricular global longitudinal strain in 513 healthy fetuses measured by two-dimensional speckle-tracking echocardiography: a multi-institutional cohort study.二维斑点追踪超声心动图测量513例健康胎儿心室整体纵向应变的正常数值及分布：一项多机构队列研究
Heart Vessels. 2025 May;40(5):414-425. doi: 10.1007/s00380-024-02477-4. Epub 2024 Oct 30.
4
Fetal Right Heart Strain in Systemic Right Ventricles and Impact on Post-surgical Outcomes.系统性右心室中的胎儿右心应变及其对术后结局的影响。
Pediatr Cardiol. 2024 Aug 9. doi: 10.1007/s00246-024-03607-5.
5
Myocardial biomechanical effects of fetal aortic valvuloplasty.胎儿主动脉瓣成形术对心肌力学的影响。
Biomech Model Mechanobiol. 2024 Oct;23(5):1433-1448. doi: 10.1007/s10237-024-01848-0. Epub 2024 Apr 29.
6
Advanced imaging of fetal cardiac function.胎儿心脏功能的高级成像
Front Cardiovasc Med. 2023 May 23;10:1206138. doi: 10.3389/fcvm.2023.1206138. eCollection 2023.
7
Characteristics and outcomes of fetal ventricular aneurysm and diverticulum: combining the use of a new technique, fetal HQ.胎儿心室动脉瘤和憩室的特征与结局：结合使用新技术——胎儿HQ
Front Pediatr. 2023 May 4;11:1165972. doi: 10.3389/fped.2023.1165972. eCollection 2023.
8
Evaluation of right ventricular myocardial deformation properties in fetal hypoplastic left heart by two-dimensional speckle tracking echocardiography.二维斑点追踪超声心动图评价胎儿左心发育不良的右心室心肌变形功能。
Arch Gynecol Obstet. 2023 Mar;307(3):699-708. doi: 10.1007/s00404-022-06857-x. Epub 2023 Feb 10.
9
Feasibility of 4D-Spatio Temporal Image Correlation (STIC) in the Comprehensive Assessment of the Fetal Heart Using FetalHQ.使用FetalHQ通过四维时空图像相关技术（STIC）全面评估胎儿心脏的可行性。
J Clin Med. 2022 Mar 4;11(5):1414. doi: 10.3390/jcm11051414.
10
Fetal myocardial deformation measured with two-dimensional speckle-tracking echocardiography: longitudinal prospective cohort study of 124 healthy fetuses.二维斑点追踪超声心动图测量胎儿心肌变形：124 例健康胎儿的纵向前瞻性队列研究。
Ultrasound Obstet Gynecol. 2022 May;59(5):651-659. doi: 10.1002/uog.24781. Epub 2022 Apr 6.
本文引用的文献
1
Relation of myocardial mechanics in severe aortic stenosis to left ventricular ejection fraction and response to aortic valve replacement.严重主动脉瓣狭窄患者心肌力学与左心室射血分数的关系及其对主动脉瓣置换术的反应。
Am J Cardiol. 2011 Apr 1;107(7):1052-7. doi: 10.1016/j.amjcard.2010.11.032. Epub 2011 Feb 4.
2
Assessment of myocardial deformation in children using Digital Imaging and Communications in Medicine (DICOM) data and vendor independent speckle tracking software.使用数字成像和通信在医学（DICOM）数据和供应商独立的斑点跟踪软件评估儿童的心肌变形。
J Am Soc Echocardiogr. 2011 Jan;24(1):37-44. doi: 10.1016/j.echo.2010.09.018. Epub 2010 Nov 20.
3
Assessment of regional right ventricular longitudinal functions in fetus using velocity vector imaging technology.应用速度向量成像技术评估胎儿右心室局部纵向功能。
Prenat Diagn. 2010 Nov;30(11):1057-63. doi: 10.1002/pd.2611.
4
Temporal and spatial performance of vector velocity imaging in the human fetal heart.胎儿心脏向量速度成像的时-空间性能。
Ultrasound Obstet Gynecol. 2011 Feb;37(2):150-7. doi: 10.1002/uog.8815.
5
The making of fetal surgery.胎儿手术的制作。
Prenat Diagn. 2010 Jul;30(7):653-67. doi: 10.1002/pd.2571.
6
Prospective assessment of fetal cardiac function with speckle tracking in healthy fetuses and recipient fetuses of twin-to-twin transfusion syndrome.应用斑点追踪技术对健康胎儿及双胎输血综合征受血儿胎儿心功能的前瞻性评估。
J Am Soc Echocardiogr. 2010 Mar;23(3):301-8. doi: 10.1016/j.echo.2009.12.024.
7
Velocity vector imaging in the measurement of left ventricular twist mechanics: head-to-head one way comparison between speckle tracking echocardiography and velocity vector imaging.速度向量成像测量左心室扭转力学：斑点追踪超声心动图与速度向量成像的头对头比较。
J Am Soc Echocardiogr. 2009 Dec;22(12):1344-52. doi: 10.1016/j.echo.2009.09.002. Epub 2009 Oct 14.
8
Evaluation of regional left ventricular longitudinal function in 151 normal fetuses using velocity vector imaging.速度向量成像技术评价 151 例正常胎儿左心室长轴功能。
Prenat Diagn. 2009 Dec;29(12):1149-55. doi: 10.1002/pd.2386.
9
Predictors of technical success and postnatal biventricular outcome after in utero aortic valvuloplasty for aortic stenosis with evolving hypoplastic left heart syndrome.对于合并进行性左心发育不全综合征的主动脉狭窄，宫内主动脉瓣成形术后技术成功及出生后双心室转归的预测因素。
Circulation. 2009 Oct 13;120(15):1482-90. doi: 10.1161/CIRCULATIONAHA.109.848994. Epub 2009 Sep 28.
10
Ventricular function in patients with transposition of the great arteries operated with arterial switch.接受动脉调转术治疗的大动脉转位患者的心室功能
Am J Cardiol. 2009 Aug 15;104(4):583-9. doi: 10.1016/j.amjcard.2009.04.029. Epub 2009 Jun 18.
Zotero 插件