Pernaa K, Koski I, Mattila K, Gullichsen E, Heikkila J, Aho A, Lindfors Nina
Department of Orthopedics and Traumatology, Turku University Hospital, Turku, Finland.
J Long Term Eff Med Implants. 2011;21(2):139-48. doi: 10.1615/jlongtermeffmedimplants.v21.i2.40.
The clinical and radiological outcomes of bioactive glass (BAG)-S53P4 and autograft bone (AB) used as bone-graft substitutes in depressed tibial plateau fractures were evaluated in a prospective randomized 11-year follow-up study. All patients (n = 29) had sustained tibial plateau fractures with a joint-line depression of >3 mm. Fifteen patients (5 patients the BAG group, 10 patients in the AB group) participated in this long-term follow-up. X-rays were taken preoperatively, postoperatively, and at the long-term follow-up, and computed tomography (CT) scans were made at the long-term follow-up for evaluation of the bone substitute, osteoarthritis, the tibial-femoral angle, and deviation of mechanical axes. No material-dependent adverse effects were seen in any patient. The means of the articular surface depression on X-rays at the long-term follow-up were 1.4 mm (range: 0-2 mm) in the BAG group and 1.4 mm (range: 0-4 mm) in the AB group, and on CT scans the means were 2.2 mm (range: 2-3 mm), and 2.1 mm (range: 0-3), respectively. No significant difference in the tibial-femoral angle or deviation of mechanical axes was observed between the two groups. BAG-S53P4 can be used as a bone substitute in depressed lateral tibial plateau fractures with good functional and radiological long-term results.
在一项前瞻性随机11年随访研究中，评估了生物活性玻璃（BAG）-S53P4和自体骨（AB）作为胫骨平台凹陷骨折骨移植替代物的临床和放射学结果。所有患者（n = 29）均发生胫骨平台骨折，关节面凹陷>3 mm。15名患者（BAG组5例，AB组10例）参与了此次长期随访。在术前、术后及长期随访时拍摄X线片，并在长期随访时进行计算机断层扫描（CT），以评估骨替代物、骨关节炎、胫股角和机械轴偏差。未在任何患者中观察到与材料相关的不良反应。长期随访时，BAG组X线片上关节面凹陷的平均值为1.4 mm（范围：0 - 2 mm），AB组为1.4 mm（范围：0 - 4 mm）；CT扫描时，平均值分别为2.2 mm（范围：2 - 3 mm）和2.1 mm（范围：0 - 3 mm）。两组之间在胫股角或机械轴偏差方面未观察到显著差异。BAG-S53P4可作为胫骨外侧平台凹陷骨折的骨替代物，具有良好的长期功能和放射学效果。
