肾移植后的血清促红细胞生成素活性
Serum erythropoietin activity following kidney transplantation.
作者信息
Vedovato M, Salvatorelli G, De Paoli Vitali E, Farinelli A, Limone G L, Panzavolta R
机构信息
Istituto di Anatomia Comparata, Universitá di Ferrara, Italy.
出版信息
Haematologia (Budap). 1990;23(1):21-5.
31 patients with successful kidney grafts were studied. Ep, Ht, Hb and T lymphocytes were determined. Native and grafted kidneys were studied by ultrasonography. After KT, 45% of patients had PTE and in 71% of these a spontaneous regression was observed. Mean serum Ep activity in patients with and without PTE was significantly higher than in healthy controls. Different erythroid colony growth sensibility and responsiveness to higher serum Ep (PTE and non-PTE patients) may be due to T3 cell interaction with BFU-E.
对31例肾移植成功的患者进行了研究。测定了促红细胞生成素（Ep）、血细胞比容（Ht）、血红蛋白（Hb）和T淋巴细胞。通过超声检查对自体肾和移植肾进行了研究。肾移植术后，45%的患者发生移植后红细胞增多症（PTE），其中71%观察到自发缓解。有PTE和无PTE患者的平均血清Ep活性均显著高于健康对照组。不同的红系集落生长敏感性以及对更高血清Ep的反应性（PTE和非PTE患者）可能归因于T3细胞与爆式红系集落形成单位（BFU-E）的相互作用。
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