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本文引用的文献

1
Cancer statistics in Korea: incidence, mortality and survival in 2005.韩国癌症统计数据：2005 年的发病率、死亡率和生存率。
J Korean Med Sci. 2009 Dec;24(6):995-1003. doi: 10.3346/jkms.2009.24.6.995. Epub 2009 Nov 7.
2
Relation between obesity and adenomatous polyps of the large bowel.肥胖与大肠腺瘤性息肉之间的关系。
Dig Endosc. 2009 Jul;21(3):154-7. doi: 10.1111/j.1443-1661.2009.00877.x.
3
American College of Gastroenterology guidelines for colorectal cancer screening 2009 [corrected].美国胃肠病学会2009年结直肠癌筛查指南[修订版]
Am J Gastroenterol. 2009 Mar;104(3):739-50. doi: 10.1038/ajg.2009.104. Epub 2009 Feb 24.
4
Association between body mass index and colorectal neoplasia at follow-up colonoscopy: a pooling study.随访结肠镜检查时体重指数与结直肠肿瘤的关联：一项汇总研究。
Am J Epidemiol. 2009 Mar 15;169(6):657-66. doi: 10.1093/aje/kwn401. Epub 2009 Jan 15.
5
An association between colonic adenoma and abdominal obesity: a cross-sectional study.结肠腺瘤与腹部肥胖之间的关联：一项横断面研究。
BMC Gastroenterol. 2009 Jan 15;9:4. doi: 10.1186/1471-230X-9-4.
6
The effect of body weight reduction on the incidence of colorectal adenoma.体重减轻对结直肠腺瘤发病率的影响。
Am J Gastroenterol. 2008 Aug;103(8):2061-7. doi: 10.1111/j.1572-0241.2008.01936.x.
7
Genotypes and haplotypes of beta2-adrenergic receptor and parameters of the metabolic syndrome in Korean adolescents.韩国青少年β2-肾上腺素能受体的基因型和单倍型与代谢综合征参数
Metabolism. 2008 Aug;57(8):1064-70. doi: 10.1016/j.metabol.2008.03.009.
8
Association between BMI and metabolic syndrome and adenomatous colonic polyps in Korean men.韩国男性体重指数与代谢综合征及结肠腺瘤性息肉之间的关联。
Obesity (Silver Spring). 2008 Jun;16(6):1434-9. doi: 10.1038/oby.2008.216. Epub 2008 Apr 3.
9
Dietary intake and the development of the metabolic syndrome: the Atherosclerosis Risk in Communities study.饮食摄入与代谢综合征的发生：社区动脉粥样硬化风险研究
Circulation. 2008 Feb 12;117(6):754-61. doi: 10.1161/CIRCULATIONAHA.107.716159. Epub 2008 Jan 22.
10
Is metabolic syndrome a risk factor for colorectal adenoma?代谢综合征是结肠直肠腺瘤的危险因素吗？
Cancer Epidemiol Biomarkers Prev. 2007 Aug;16(8):1543-6. doi: 10.1158/1055-9965.EPI-07-0199.

代谢综合征、生活方式风险因素与远端结肠腺瘤：一项回顾性队列研究。

Metabolic syndrome, lifestyle risk factors, and distal colon adenoma: a retrospective cohort study.

机构信息

Department of Family Medicine, Ulsan University Hospital, University of Ulsan College of Medicine, Ulsan 682-714, South Korea.

出版信息

World J Gastroenterol. 2011 Sep 21;17(35):4031-7. doi: 10.3748/wjg.v17.i35.4031.

DOI:10.3748/wjg.v17.i35.4031
PMID:22046093
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3199563/
Abstract

AIM

To investigate relationships between colorectal adenoma incidence, metabolic syndrome (MS) components and lifestyle factors.

METHODS

We conducted a retrospective cohort study using data from individuals who had multiple sigmoidoscopies for colon cancer at the Health Promotion Center of Ulsan University Hospital in Korea from 1998 to 2007.

RESULTS

By multivariate analysis, the incidence of distal colon adenoma was increased by more than 1.76 times in individuals with at least one component of MS compared to those without a component of MS. After adjustment for age, gender, smoking, drinking, and physical exercise, only high body mass index (BMI) was significantly associated with the incidence of distal colon adenoma (Hazard ratio 1.66, 95% confidence interval 1.05-2.62).

CONCLUSION

Our results suggest that high BMI may increase the risk of colorectal adenoma in Korean adults.

摘要

目的

探讨结直肠腺瘤发病率、代谢综合征（MS）成分与生活方式因素之间的关系。

方法

我们使用韩国蔚山大学医院健康促进中心在 1998 年至 2007 年间对因结肠癌多次进行乙状结肠镜检查的个体的数据进行了回顾性队列研究。

结果

通过多变量分析，与无 MS 成分的个体相比，至少存在一种 MS 成分的个体远端结肠腺瘤的发病率增加了 1.76 倍以上。在调整年龄、性别、吸烟、饮酒和体育锻炼后，只有高体重指数（BMI）与远端结肠腺瘤的发病率显著相关（危险比 1.66，95%置信区间 1.05-2.62）。

结论

我们的结果表明，高 BMI 可能会增加韩国成年人结直肠腺瘤的风险。