Department of Ophthalmology, Clínica Universidad de Navarra, Pamplona, Spain.
J Glaucoma. 2013 Mar;22(3):243-9. doi: 10.1097/IJG.0b013e318237c878.
The purpose of the study was to evaluate the influence of the examiner's experience on the reproducibility of retinal nerve fiber layer (RNFL) measurements obtained with Cirrus optical coherence tomography (OCT) and Stratus.
Fifty-one normal and glaucomatous eyes of 51 participants were included. Two examiners (1 novice, 1 experienced) obtained 2 scans using both OCTs. For quantitative measurements, Bland and Altman limits of agreement were evaluated. For qualitative classifications, κ coefficients were calculated.
Signal strength was higher with Cirrus than with Stratus (P<0.05). Signal strength was higher in scans performed by the experienced examiner than in those carried out by the inexperienced examiner in Stratus but not in Cirrus. RNFL measurement differences between Cirrus and Stratus were influenced by the examiner for the inferior (P=0.02), superior (P<0.001), and temporal quadrants (P=0.009). The RNFL quantitative agreement of examiners was higher in Cirrus than in Stratus. The qualitative agreement (κ coefficients) of both examiners in the RNFL classification were almost perfect with Cirrus (in the average, superior, and inferior quadrants), and moderate with Stratus (only in average and inferior quadrant).
The signal strength is independent of the examiner's experience in Cirrus but not in Stratus. RNFL measurements obtained by both examiners were more reproducible with Cirrus than with Stratus. The differences in RNFL measurements between both OCTs were related to the examiner's experience in all 3 quadrants. Agreement between operators in the RNFL classification was higher with Cirrus than Stratus.
本研究旨在评估检查者经验对 Cirrus 光学相干断层扫描(OCT)和 Stratus 获得的视网膜神经纤维层(RNFL)测量值重复性的影响。
纳入 51 名正常和青光眼参与者的 51 只眼。两名检查者(1 名新手,1 名经验丰富者)使用两种 OCT 各进行 2 次扫描。对于定量测量,评估了 Bland 和 Altman 一致性界限。对于定性分类,计算了 κ 系数。
Cirrus 的信号强度高于 Stratus(P<0.05)。在 Stratus 中,经验丰富的检查者进行的扫描信号强度高于经验不足的检查者,但 Cirrus 中则不然。Cirrus 和 Stratus 之间的 RNFL 测量差异受检查者影响,以下方(P=0.02)、上方(P<0.001)和颞方(P=0.009)象限为甚。检查者在 Cirrus 中的 RNFL 定量一致性高于 Stratus。两名检查者在 Cirrus 中的 RNFL 分类定性一致性(κ 系数)几乎为完美(平均、上方和下方象限),在 Stratus 中则为中度(仅在平均和下方象限)。
Cirrus 中的信号强度与检查者的经验无关,但 Stratus 则不然。两名检查者使用 Cirrus 和 Stratus 获得的 RNFL 测量值的重复性更高。两种 OCT 之间的 RNFL 测量值差异与所有 3 个象限中检查者的经验有关。在 RNFL 分类中,操作者之间的一致性在 Cirrus 中高于 Stratus。