Tong B Y, Battersby S J
Nucleic Acids Res. 1979 Mar;6(3):1073-9. doi: 10.1093/nar/6.3.1073.
When the theoretical denaturation maps of phiX174 and SV40 are compared with their gene maps, it is observed that the beginning and the end of each gene in these two DNA's fall in a region of lower melting temperatures. Local (A+T)-contents evaluated from the known sequences at these regions support the above implication that the beginnings and the ends of nearly all the genes in phiX174 and SV40 are relatively rich in (A+T)-content.
当将φX174和SV40的理论变性图谱与其基因图谱进行比较时,可以观察到这两种DNA中每个基因的起始和末端都位于较低解链温度的区域。从这些区域的已知序列评估的局部(A+T)含量支持上述观点,即φX174和SV40中几乎所有基因的起始和末端(A+T)含量相对较高。