Dipartimento di Scienze e Tecnologie Alimentari e Microbiologiche, sezione Nutrizione, Via Celoria 2, Università degli Studi di Milano, 20133 Milano, Italy.
J Agric Food Chem. 2011 Dec 28;59(24):12815-20. doi: 10.1021/jf2028686. Epub 2011 Nov 18.
Wild blueberries are a rich source of polyphenols and other compounds that are highly metabolized by the intestinal microbiota and may, at the same time, affect the intestinal environment itself. A repeated-measure, crossover dietary intervention on human volunteers was designed to study the effect of six week consumption of a wild blueberry ( Vaccinium angustifolium ) drink, versus a placebo drink, in modulating the intestinal microbiota. Relative to total eubacteria, Bifidobacterium spp. significantly increased following blueberry treatment (P ≤ 0.05), while Lactobacillus acidophilus increased after both treatments (P ≤ 0.05). No significant differences were observed for Bacteroides spp., Prevotella spp., Enterococcus spp., and Clostridium coccoides . Bifidobacteria, which have been largely proposed to be of benefit for the host, appeared to be selectively favored suggesting an important role for the polyphenols and fiber present in wild blueberries. Results obtained suggest that regular consumption of a wild blueberry drink can positively modulate the composition of the intestinal microbiota.
野生蓝莓是多酚和其他化合物的丰富来源，这些化合物高度代谢肠道微生物群，同时可能影响肠道环境本身。在人类志愿者中进行了一项重复测量、交叉饮食干预研究，以研究六周内饮用野生蓝莓（Vaccinium angustifolium）饮料与安慰剂饮料对肠道微生物群的调节作用。与总真细菌相比，双歧杆菌属在蓝莓处理后显著增加（P≤0.05），而嗜酸乳杆菌在两种处理后均增加（P≤0.05）。拟杆菌属、普雷沃氏菌属、肠球菌属和梭菌属没有观察到显著差异。双歧杆菌被广泛认为对宿主有益，似乎被选择性地青睐，这表明野生蓝莓中存在的多酚和纤维具有重要作用。研究结果表明，经常饮用野生蓝莓饮料可以积极调节肠道微生物群的组成。
