Romero Sandra Adolfina Reyes, Pereira Priscilla Maria Rodrigues, Mariano Adriana Valkiria de Oliveira, Francesconi Fábio, Francesconi Valeska Albuquerque
Hospital Universitário Getúlio Vargas, Universidade Federal do Amazonas, Manaus, AM, Brasil.
An Bras Dermatol. 2011 Jul-Aug;86(4 Suppl 1):S31-4. doi: 10.1590/s0365-05962011000700007.
Exogenous ochronosis consists of chronic hyperpigmentation of areas previously treated with topical agents such as hydroquinone, resorcinol, antimalarials and phenol. Early diagnosis allows to promptly suspend the causative agent and it is imperative since the available therapeutic options are scarce and have presented so far unsatisfactory results. Three cases of exogenous ochronosis on the face which were diagnosed with the use of dermoscopy are presented. Dermatoscopy showed blackish-gray amorphous structures, some obliterating the follicular openings. Histopathological examination confirmed the diagnosis.
外源性褐黄病表现为先前使用对苯二酚、间苯二酚、抗疟药和苯酚等外用制剂治疗过的部位出现慢性色素沉着。早期诊断有助于迅速停用致病药物,这一点至关重要,因为目前可用的治疗选择有限,且迄今为止效果并不理想。本文报告了3例经皮肤镜诊断的面部外源性褐黄病病例。皮肤镜检查显示为黑灰色无定形结构,部分堵塞毛囊开口。组织病理学检查证实了诊断。