中心性浆液性脉络膜视网膜病变的近红外自发荧光和吲哚菁绿血管造影。
Near-infrared autofluorescence and indocyanine green angiography in central serous chorioretinopathy.
机构信息
Department of Ophthalmology, General Hospital Klagenfurt, Klagenfurt, Austria.
出版信息
Ophthalmologica. 2012;227(1):34-8. doi: 10.1159/000331987. Epub 2011 Nov 10.
PURPOSE
To evaluate the diagnostic potential of near-infrared (NIR) autofluorescence (AF) in central serous chorioretinopathy (CSC) and to present a method to analyze NIR-AF findings quantitatively.
PROCEDURES
NIR-AF images, indocyanine green (ICG) angiograms, blue-light autofluorescence (BL-AF) images and fluorescein angiograms were recorded with the use of a confocal scanning laser ophthalmoscope in 19 eyes of 17 patients with CSC. Gray-value ratios were calculated to compare the methods.
RESULTS
Using NIR-AF, hypofluorescent spots were observed at the leakage site in 18 of 19 eyes (94.7%). The mean gray-value ratio (±SD) was 0.55 ± 0.22 for the site of the leakage point with NIR-AF and 0.65 ± 0.35 with BL-AF. ICG angiography showed a gray-value ratio of 2.37 ± 2.07. Fluorescein angiography had the best contrast, with a gray-value ratio of 13.44 ± 15.02.
CONCLUSION
NIR-AF demonstrated CSC in 94.7% of the cases. NIR-AF may be a noninvasive alternative to detect CSC.
目的
评估近红外（NIR）自发荧光（AF）在中心性浆液性脉络膜视网膜病变（CSC）中的诊断潜力，并提出一种定量分析 NIR-AF 结果的方法。
方法
使用共焦扫描激光检眼镜对 17 例 19 只眼的 CSC 患者进行 NIR-AF 图像、吲哚菁绿（ICG）血管造影、蓝光自发荧光（BL-AF）图像和荧光素血管造影检查。计算灰度比值以比较这些方法。
结果
在 19 只眼中，18 只（94.7%）眼在渗漏部位观察到低荧光点。NIR-AF 渗漏点的平均灰度比值（±SD）为 0.55±0.22，BL-AF 为 0.65±0.35。ICG 血管造影的灰度比值为 2.37±2.07。荧光素血管造影具有最佳的对比度，灰度比值为 13.44±15.02。
结论
NIR-AF 显示 CSC 的病例占 94.7%。NIR-AF 可能是一种非侵入性替代方法，用于检测 CSC。
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