Department of Obstetrics and Gynecology, Beijing Shijitan Hospital, Capital Medical University, Beijing, China.
Department of Clinical Medicine, Xiangya School of Medicine, Central South University, Hunan, China.
Maturitas. 2018 May;111:77-81. doi: 10.1016/j.maturitas.2018.01.019. Epub 2018 Feb 2.
To observe the hearing function around menopause, to analyze the effects of ovarian reserve and hormone therapy on hearing, and to study factors related to hearing loss among women around menopause.
In this cross-sectional study, we evaluated 109 women around menopause aged 45-55 years, including 40 women with ovarian failure, 48 with ovarian non-failure, and 21 receiving hormone therapy. All women underwent an audiologic evaluation, and hormone blood testing was performed. The general condition, reproductive history, medical history, lifestyle, and menopausal symptoms were collected through a questionnaire.
The auditory threshold and anti-Mullerian hormone level.
Women in the ovarian failure group presented with a decreased hearing level in all frequency bands compared with those in the ovarian non-failure group; the significant differences occurred at 8000 Hz, 10 000 Hz, 12 500 Hz, and 16 000 Hz in the right-ear air conduction. The auditory threshold was lower in the hormone therapy group than in the ovarian failure group, but the difference was statistically significant only in the right-ear air conduction at 10 000 Hz. There were two risk factors for hearing loss: an anti-Mullerian hormone level <0.01 ng/mL (odds ratio [OR] = 2.624) and frequent earphone use (OR = 3.846).
A decline in ovarian function is associated with hearing loss in women, especially in relation to extended high-frequency air conduction of the right ear. Preserving ovarian function and reducing earphone use are important measures to protect women's hearing. However, the effect of hormone therapy on hearing requires further investigation.
观察围绝经期听力功能，分析卵巢储备功能及激素治疗对听力的影响，研究围绝经期妇女听力损失的相关因素。
本横断面研究评估了 109 名 45-55 岁围绝经期女性，包括 40 名卵巢衰竭女性、48 名卵巢非衰竭女性和 21 名接受激素治疗的女性。所有女性均进行了听力学评估，并进行了激素血液检测。通过问卷调查收集了一般情况、生育史、病史、生活方式和绝经症状。
听阈和抗苗勒管激素水平。
卵巢衰竭组女性所有频率的听力水平均低于卵巢非衰竭组；右耳空气传导在 8000 Hz、10 000 Hz、12 500 Hz 和 16 000 Hz 时差异有统计学意义。激素治疗组的听阈低于卵巢衰竭组，但仅在右耳空气传导 10 000 Hz 时差异有统计学意义。听力损失的两个危险因素是抗苗勒管激素水平<0.01ng/ml（比值比[OR] = 2.624）和频繁使用耳机（OR = 3.846）。
卵巢功能下降与女性听力下降有关，尤其是与右耳高频空气传导有关。保护卵巢功能和减少耳机使用是保护女性听力的重要措施。然而，激素治疗对听力的影响需要进一步研究。
