Department of Cardiology and Cardiovascular Surgery, Clínica Universidad de Navarra, Avenida de Pio XII, 36. 31008 Pamplona, Navarra, Spain.
BMC Public Health. 2011 Nov 15;11:867. doi: 10.1186/1471-2458-11-867.
The objective of this study was to evaluate the validity of self reported criteria of Metabolic Syndrome (MS) in the SUN (Seguimiento Universidad de Navarra) cohort using their medical records as the gold standard.
We selected 336 participants and we obtained MS related data according to Adult Treatment Panel III (ATP III) and International Diabetes Federation (IDF). Then we compared information on the self reported diagnosis of MS and MS diagnosed in their medical records. We calculated the proportion of confirmed MS, the proportion of confirmed non-MS and the intraclass correlation coefficients for each component of the MS.
From those 336 selected participants, we obtained sufficient data in 172 participants to confirm or reject MS using ATP III criteria. The proportion of confirmed MS was 91.2% (95% CI: 80.7- 97.1) and the proportion of confirmed non-MS was 92.2% (95% CI: 85.7-96.4) using ATP III criteria. The proportion of confirmed MS using IDF criteria was 100% (95% CI: 87.2-100) and the proportion of confirmed non-MS was 97.1% (95% CI: 85.1-99.9). Kappa Index was 0.82 in the group diagnosed by ATP III criteria and 0.97 in the group diagnosed by IDF criteria. Intraclass correlation coefficients for the different component of MS were: 0.93 (IC 95%:0.91- 0.95) for BMI; 0.96 (IC 95%: 0.93-0.98) for waist circumference; 0.75 (IC 95%: 0.66-0.82) for fasting glucose; 0.50 (IC 95%:0.35-0.639) for HDL cholesterol; 0.78 (IC 95%: 0.70-0.84) for triglycerides; 0.49 (IC 95%:0.34-0.61) for systolic blood pressure and 0.55 (IC 95%: 0.41-0.65) for diastolic blood pressure.
Self-reported MS based on self reported components of the SM in a Spanish cohort of university graduates was sufficiently valid as to be used in epidemiological studies.
本研究旨在评估基于代谢综合征（Metabolic Syndrome，MS）自我报告标准的大学生队列研究（SUN）中自我报告的有效性，将其医疗记录作为金标准。
我们选择了 336 名参与者，并根据成人治疗小组 III（Adult Treatment Panel III，ATP III）和国际糖尿病联合会（International Diabetes Federation，IDF）获得了与 MS 相关的数据。然后，我们比较了自我报告的 MS 诊断和医疗记录中诊断的 MS 之间的信息。我们计算了 MS 的每个组成部分的确诊 MS 比例、确诊非 MS 比例和组内相关系数。
从这 336 名选定的参与者中，我们从 172 名参与者中获得了足够的数据，根据 ATP III 标准确定或排除 MS。使用 ATP III 标准，确诊 MS 的比例为 91.2%（95%可信区间：80.7-97.1），确诊非 MS 的比例为 92.2%（95%可信区间：85.7-96.4）。使用 IDF 标准，确诊 MS 的比例为 100%（95%可信区间：87.2-100），确诊非 MS 的比例为 97.1%（95%可信区间：85.1-99.9）。根据 ATP III 标准诊断的组中，Kappa 指数为 0.82，根据 IDF 标准诊断的组中，Kappa 指数为 0.97。MS 不同组成部分的组内相关系数分别为：体重指数（BMI）为 0.93（IC 95%：0.91-0.95）；腰围为 0.96（IC 95%：0.93-0.98）；空腹血糖为 0.75（IC 95%：0.66-0.82）；高密度脂蛋白胆固醇为 0.50（IC 95%：0.35-0.639）；甘油三酯为 0.78（IC 95%：0.70-0.84）；收缩压为 0.49（IC 95%：0.34-0.61）；舒张压为 0.55（IC 95%：0.41-0.65）。
基于西班牙大学生队列研究中代谢综合征自我报告的自我报告成分的 MS 自我报告，在流行病学研究中具有足够的有效性，可以使用。
