纤连蛋白包被种植体对犬骨整合的影响。
The effect of fibronectin-coated implant on canine osseointegration.
作者信息
Kim Sungtae, Myung Woo-Chun, Lee Jung-Seok, Cha Jae-Kook, Jung Ui-Won, Yang Hyeong-Cheol, Lee In-Seop, Choi Seong-Ho
机构信息
Department of Prosthodontics, Yonsei University College of Dentistry, Seoul, Korea.
出版信息
J Periodontal Implant Sci. 2011 Oct;41(5):242-7. doi: 10.5051/jpis.2011.41.5.242. Epub 2011 Oct 31.
PURPOSE
The purpose of this study was to characterize the osseointegration of the fibronectin-coated implant surface.
METHODS
Sand-blasted, large-grit, acid-etched (SLA) surface implants, with or without a thin calcium phosphate and fibronectin coating, were placed in edentulous mandibles of dogs 8 weeks after extraction. All dogs were sacrificed forhistological and histomorphometric evaluation after 4- and 8-week healing periods.
RESULTS
All types of implants were clinically stable without any mobility. Although the bone-to-implant contact and bone density of the SLA implants coated with calcium phosphate (CaP)/fibronectin were lower than the uncoated SLA implants, there were no significant differences between the uncoated SLA surface group and the SLA surface coated with CaP/fibronectin group.
CONCLUSIONS
Within the limits of this study, SLA surfaces coated with CaP/fibronectin were shown to have comparable bone-to-implant contact and bone density to uncoated SLA surfaces.
目的
本研究的目的是表征纤连蛋白涂层种植体表面的骨整合情况。
方法
将经过喷砂、大颗粒酸蚀（SLA）处理的表面种植体，有或没有薄磷酸钙和纤连蛋白涂层，在拔牙8周后植入犬的无牙下颌骨。在4周和8周愈合期后，处死所有犬进行组织学和组织形态计量学评估。
结果
所有类型的种植体在临床上均稳定，无任何松动。虽然涂有磷酸钙（CaP）/纤连蛋白的SLA种植体的骨-种植体接触和骨密度低于未涂层的SLA种植体，但未涂层的SLA表面组和涂有CaP/纤连蛋白的SLA表面组之间没有显著差异。
结论
在本研究的范围内，涂有CaP/纤连蛋白的SLA表面显示出与未涂层的SLA表面具有相当的骨-种植体接触和骨密度。
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