Chengdu Institute of Biology, Chinese Academy of Sciences, Chengdu 610041, China.
Chem Commun (Camb). 2012 Jan 7;48(2):305-7. doi: 10.1039/c1cc14640h. Epub 2011 Nov 17.
The first transition-metal-catalyzed direct oxidative synthesis of amides by using dioxygen as an oxygen source has been developed under mild conditions, in which DBU was used as the key additive. The present methodology, which utilizes dioxygen as an oxidant and oxygen source and cheap copper salts as catalysts, opens up an interesting and attractive avenue for the synthesis of amide functionality.
首次发展了在温和条件下，以氧气为氧源，利用第一过渡金属催化剂直接氧化合成酰胺的方法，其中 DBU 被用作关键添加剂。本方法利用氧气作为氧化剂和氧源，以及廉价的铜盐作为催化剂，为酰胺官能团的合成开辟了一条有趣且有吸引力的途径。
