Department of Orthopaedic Surgery, Istituto Ortopedico Rizzoli, University of Bologna, Via G.C. Pupilli 1, 40136, Bologna, Italy.
J Orthop Traumatol. 2011 Dec;12(4):201-5. doi: 10.1007/s10195-011-0169-4. Epub 2011 Nov 17.
In an effort to avoid the morbidity associated with autogenous bone graft harvesting, cervical cages in combination with allograft bone are used to achieve fusion. The goal of the current study was to assess the reliability and efficacy of anterior cervical discectomy and interbody fusion (ACDF) using a PEEK anatomical cervical cage in the treatment of patients affected by single-level cervical degenerative disease.
Twenty-five patients affected by single-level cervical degenerative pathology between C4 and C7 were enrolled in this study. The clinical findings were assessed using the Neck Disability Index and the Visual Analog Scale. Surgical outcomes were rated according to Odom's criteria at last follow-up. Fusion was graded as poor, average, good or excellent by assessing the radiographs. Cervical spine alignment was evaluated by sagittal segmental alignment and sagittal alignment of the whole cervical spine preoperatively, 6 months postoperatively and at the last follow-up.
Twenty-five patients underwent ACDF using a PEEK anatomical cervical cage. All patients had a minimum 2 years of follow-up. The operative levels were C4-C5 in 5 patients, C5-C6 in 12 patients and C6-C7 in 8 patients. Preoperatively, average NDI was 34, 13 at 6 months, and 10 at latest follow-up. The mean preoperative VAS was 7; the mean postoperative VAS at latest follow-up was 3. Good or excellent fusion was achieved in all patients within 10 months (mean 5 months). Preoperatively, average sagittal segmental alignment (SSA) was 0.2° and average sagittal alignment of the cervical spine (SACS) 15.8°. Six months after surgery, average SSA was 1.8° and average SACS 20.9°, and at last follow-up, average SSA was 1.6° and average SACS 18.5°.
Anterior cervical discectomy and interbody fusion using PEEK anatomical cervical cages can be considered a safe and effective technique to cure cervical disc herniation with intractable pain or neural deficit in cases where conservative treatment failed.
为避免自体骨移植采集带来的发病率，颈椎融合器与同种异体骨联合使用以实现融合。本研究的目的是评估 PEEK 解剖颈椎融合器在前路颈椎间盘切除融合术（ACDF）治疗单节段颈椎退行性疾病患者中的可靠性和疗效。
本研究纳入了 25 例 C4 至 C7 单节段颈椎退行性病变患者。采用颈部残疾指数和视觉模拟评分评估临床结果。末次随访时，根据 Odom 标准对手术结果进行评分。通过评估 X 线片，融合被评为差、中、优或极好。术前、术后 6 个月和末次随访时，通过矢状节段性排列和整个颈椎矢状位排列评估颈椎脊柱排列。
25 例患者采用 PEEK 解剖颈椎融合器行 ACDF。所有患者均随访至少 2 年。手术节段为 C4-C5 者 5 例，C5-C6 者 12 例，C6-C7 者 8 例。术前，平均 NDI 为 34，术后 6 个月为 13，末次随访时为 10。术前 VAS 平均为 7，末次随访时平均为 3。10 个月（平均 5 个月）内所有患者均获得良好或极好的融合。术前平均矢状节段性排列（SSA）为 0.2°，颈椎矢状排列（SACS）为 15.8°。术后 6 个月时，平均 SSA 为 1.8°，SACS 为 20.9°，末次随访时，平均 SSA 为 1.6°，SACS 为 18.5°。
前路颈椎间盘切除融合术采用 PEEK 解剖颈椎融合器是一种安全有效的技术，可用于治疗保守治疗失败后出现顽固性疼痛或神经功能缺损的颈椎间盘突出症。
