Department of Gastrointestinal Services, University College London Hospitals NHS Foundation Trust, London NW12BU, United Kingdom.
World J Gastroenterol. 2011 Oct 14;17(38):4308-13. doi: 10.3748/wjg.v17.i38.4308.
To compare high resolution colonoscopy (Olympus Lucera) with a megapixel high resolution system (Pentax HiLine) as an in-service evaluation.
Polyp detection rates and measures of performance were collected for 269 colonoscopy procedures. Five colonoscopists conducted the study over a three month period, as part of the United Kingdom bowel cancer screening program.
There were no differences in procedure duration (χ² P = 0.98), caecal intubation rates (χ² P = 0.67), or depth of sedation (χ² P = 0.64). Mild discomfort was more common in the Pentax group (χ² P = 0.036). Adenoma detection rate was significantly higher in the Pentax group (χ² test for trend P = 0.01). Most of the extra polyps detected were flat or sessile adenomas.
Megapixel definition colonoscopes improve adenoma detection without compromising other measures of endoscope performance. Increased polyp detection rates may improve future outcomes in bowel cancer screening programs.
将高分辨率结肠镜（奥林巴斯 Lucera）与百万像素高分辨率系统（宾得 HiLine）进行比较，作为一项服务评估。
对 269 例结肠镜检查进行了息肉检测率和性能评估。5 名结肠镜检查医师在三个月的时间内进行了这项研究，作为英国结直肠癌筛查计划的一部分。
手术持续时间（χ² P = 0.98）、盲肠插管率（χ² P = 0.67）或镇静深度（χ² P = 0.64）无差异。宾得组更常见轻度不适（χ² P = 0.036）。腺瘤检出率在宾得组显著更高（χ²趋势检验 P = 0.01）。检测到的大多数额外息肉为扁平或无蒂腺瘤。
百万像素定义结肠镜可提高腺瘤检出率，而不影响内镜性能的其他评估指标。增加的息肉检出率可能会提高结直肠癌筛查计划的未来结果。
