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2005年至2010年兽医放射肿瘤学手稿中放射治疗计划、剂量和实施报告的完整性

Completeness of reporting of radiation therapy planning, dose, and delivery in veterinary radiation oncology manuscripts from 2005 to 2010.

作者信息

Keyerleber Michele A, McEntee Margaret C, Farrelly John, Podgorsak Matthew

机构信息

Department of Clinical Sciences, College of Veterinary Medicine, Cornell University, Ithaca, NY 14853, USA.

出版信息

Vet Radiol Ultrasound. 2012 Mar-Apr;53(2):221-30. doi: 10.1111/j.1740-8261.2011.01882.x.

DOI:10.1111/j.1740-8261.2011.01882.x
PMID:22092592
Abstract

Surrounding a shift toward evidence-based medicine and widespread adoption of reporting guidelines such as the Consolidated Standards of Reporting Trials (CONSORT) statement, there has been a growing body of literature evaluating the quality of reporting in human and veterinary medicine. These reviews have consistently demonstrated the presence of substantive deficiencies in completeness of reporting. The purpose of this study was to assess the current status of reporting in veterinary radiation oncology manuscripts in regards to treatment planning methods, dose, and delivery and to introduce a set of reporting guidelines to serve as a standard for future reporting. Forty-six veterinary radiation oncology manuscripts published between 2005 and 2010 were evaluated for reporting of 50 items pertaining to patient data, treatment planning, radiation dose, delivery of therapy, quality assurance, and adjunctive therapy. A mean of 40% of checklist items were reported in a given manuscript (range = 8-75%). Only 9/50 (18%) checklist items were reported in > or = 80% manuscripts. The completeness of reporting was best in regards to a statement of prescription radiation protocol (91-98% reported) and worst in regards to specification of absorbed dose within target volumes and surrounding normal tissues (0-6% reported). No manuscripts met the current International Commission of Radiation Units and Measurements (ICRU) dose specification recommendations. Incomplete reporting may stem from the predominance of retrospective manuscripts and the variability of protocols and equipment in veterinary radiation oncology. Adoption of reporting guidelines as outlined in this study is recommended to improve the quality of reporting in veterinary radiation oncology.

摘要

随着向循证医学的转变以及诸如《试验报告统一标准》(CONSORT)声明等报告指南的广泛采用,评估人类和兽医学报告质量的文献越来越多。这些综述一致表明报告的完整性存在实质性缺陷。本研究的目的是评估兽医放射肿瘤学手稿中关于治疗计划方法、剂量和投照方面的报告现状,并引入一套报告指南作为未来报告的标准。对2005年至2010年间发表的46篇兽医放射肿瘤学手稿进行评估,以确定与患者数据、治疗计划、放射剂量、治疗投照、质量保证和辅助治疗相关的50项内容的报告情况。给定手稿中平均报告了40%的清单项目(范围 = 8 - 75%)。在≥80%的手稿中仅报告了9/50(18%)的清单项目。关于处方放射方案的陈述报告完整性最好(报告率为91 - 98%),而关于靶体积和周围正常组织内吸收剂量的具体说明报告完整性最差(报告率为0 - 6%)。没有手稿符合当前国际辐射单位与测量委员会(ICRU)的剂量规范建议。报告不完整可能源于回顾性手稿占主导以及兽医放射肿瘤学中方案和设备的变异性。建议采用本研究中概述的报告指南以提高兽医放射肿瘤学的报告质量。

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