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HIV感染患者慢性腹泻的管理：当前的治疗选择、挑战及未来方向

Management of chronic diarrhea in HIV-infected patients: current treatment options, challenges and future directions.

作者信息

Elfstrand Lidia, Florén Claes-Henrik

机构信息

Department of Medicine, Division of Clinical Sciences, Skåne University Hospital, Lund University, Lund, Sweden.

出版信息

HIV AIDS (Auckl). 2010;2:219-24. doi: 10.2147/HIV.S13191. Epub 2010 Nov 10.

DOI:10.2147/HIV.S13191
PMID:22096401
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3218691/
Abstract

Diarrhea is a common clinical manifestation of HIV infection regardless of whether the patients have AIDS. HIV and malnutrition tend to occur in the same populations, the underprivileged and resource-poor. Malnutrition increases severity and mortality of infection. Occurrence of chronic diarrhea in HIV-infected patients, gut status and pathogenic agents, nutritional status and the crucial role of nutrition are reviewed. Bovine colostrum-based food can be useful for managing chronic diarrhea in HIV-infected patients, enhancing both nutritional and immunological status.

摘要

腹泻是HIV感染的常见临床表现，无论患者是否患有艾滋病。HIV感染与营养不良往往发生在相同人群中，即贫困和资源匮乏人群。营养不良会增加感染的严重程度和死亡率。本文综述了HIV感染患者慢性腹泻的发生情况、肠道状况和病原体、营养状况以及营养的关键作用。以牛初乳为基础的食物可能有助于管理HIV感染患者的慢性腹泻，同时提高营养和免疫状况。

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本文引用的文献

1
Effect of bovine colostrum-based food supplement in the treatment of HIV-associated diarrhea in Northern Uganda: a randomized controlled trial.
Indian J Gastroenterol. 2011 Dec;30(6):270-6. doi: 10.1007/s12664-011-0146-0. Epub 2011 Dec 13.
2
Nutritional aspects of HIV-associated wasting in sub-Saharan Africa.撒哈拉以南非洲地区与人类免疫缺陷病毒相关的消耗的营养问题。
Am J Clin Nutr. 2010 Apr;91(4):1138S-1142S. doi: 10.3945/ajcn.2010.28608D. Epub 2010 Feb 10.
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Declines in mortality rates and changes in causes of death in HIV-1-infected children during the HAART era.抗逆转录病毒治疗时代 HIV-1 感染儿童死亡率的下降和死亡原因的变化。
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Opportunistic parasitic infections in HIV/AIDS patients presenting with diarrhoea by the level of immunesuppression.按免疫抑制水平划分的出现腹泻的艾滋病毒/艾滋病患者中的机会性寄生虫感染
Indian J Med Res. 2009 Jul;130(1):63-6.
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Macronutrient supplementation for malnourished HIV-infected adults: a review of the evidence in resource-adequate and resource-constrained settings.为营养不良的感染艾滋病毒成年人补充宏量营养素：资源充足和资源有限环境下的证据综述
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Virological efficacy and emergence of drug resistance in adults on antiretroviral treatment in rural Tanzania.坦桑尼亚农村接受抗逆转录病毒治疗的成年人的病毒学疗效及耐药性出现情况
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The effect of nutritional support on weight gain of HIV-infected children with prolonged diarrhoea.
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