欧洲铊201与锝99m甲氧基异丁基异腈在缺血性心脏病中的多中心比较。
European multi-centre comparison of thallium 201 and technetium 99m methoxyisobutylisonitrile in ischaemic heart disease.
作者信息
Maisey M N, Lowry A, Bischof-Delaloye A, Fridrich R, Inglese E, Khalil M N, van der Schoot J B
机构信息
Division of Radiological Sciences, UMDS, Guy's Hospital, London Bridge, UK.
出版信息
Eur J Nucl Med. 1990;16(12):869-72. doi: 10.1007/BF01280254.
Fifty-six patients in Europe were entered into a multi-centre study to compare the accuracy of technetium 99m methoxyisobutylisonitrile (99mTc-MIBI) for the detection of coronary artery disease (CAD) with thallium 201 (201Tl) chloride perfusion scanning. The results showed a high degree of concordance between the two radiopharmaceuticals. Some 81% (678/840) of myocardial segments showed the same result (normal, infarct or ischaemia), and 80% (45/56) of patients had the same diagnosis. Overall detection of CAD in patients was 98% for 201T1 and 96% for 99mTc-MIBI. Detection of CAD in total arteries was 68% for both agents. In this study 99mTc-MIBI was as accurate as 201Tl for the detection of coronary artery stenoses.
欧洲的56名患者参与了一项多中心研究，以比较锝99m甲氧基异丁基异腈（99mTc-MIBI）与氯化铊201（201Tl）灌注扫描检测冠状动脉疾病（CAD）的准确性。结果显示，两种放射性药物之间具有高度一致性。约81%（678/840）的心肌节段显示相同结果（正常、梗死或缺血），80%（45/56）的患者有相同诊断。患者中CAD的总体检测率201Tl为98%，99mTc-MIBI为96%。两种药物对总动脉中CAD的检测率均为68%。在这项研究中，99mTc-MIBI在检测冠状动脉狭窄方面与201Tl一样准确。
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