Department of Rheumatology, Lapeyronie Hospital, Montpellier University 1, 34295 Montpellier, France.
Best Pract Res Clin Rheumatol. 2011 Jun;25(3):337-46. doi: 10.1016/j.berh.2011.03.005.
Chikungunya virus (CHIKV) is an emerging alphavirus responsible for several infectious outbreaks in the world. After an acute stage of illness characterised by a fever-arthralgia syndrome and rash, joint disorders due to CHIKV infection can sometimes persist for several months or years. Chronic arthritis after this emerging disease is well documented, and similarities to rheumatoid arthritis have been described. Knowledge of the geographical epidemiology of CHIKV infection is crucial for better control of the disease. Thus, recent outbreaks have led to several studies, which have highlighted the need for a better understanding of the clinical features of Chikungunya (CHIK) and beginning knowledge of the pathophysiogenesis, which can lead to further research.
基孔肯雅热病毒（CHIKV）是一种新兴的甲病毒，可导致世界范围内的数次传染病暴发。在经历了以发热-关节痛综合征和皮疹为特征的急性发病期后，CHIKV 感染引起的关节疾病有时可持续数月甚至数年。这种新发疾病后出现的慢性关节炎已有明确记载，且与类风湿关节炎具有相似性。了解 CHIKV 感染的地理流行病学对于更好地控制疾病至关重要。因此，最近的暴发促使人们进行了多项研究，这些研究强调了更好地了解基孔肯雅热（CHIK）的临床特征以及发病机制基础知识的必要性，这可以进一步推动相关研究。
