Department of Acupuncture and Rehabilitation, First Hospital Affiliated to Nanjing University of Traditional Chinese Medicine, Nanjing, China.
Chin J Integr Med. 2011 Oct;17(10):780-5. doi: 10.1007/s11655-011-0875-z. Epub 2011 Nov 19.
To explore the effect of Soothing Gan and invigorating Pi (SGIP) acupuncture treatment on the clinical symptoms and quality of life (QOL) in patients with diarrhea-predominant irritable bowel syndrome (IBS-D).
With a single-blinded randomized control study adopted, 63 patients who met the inclusion criteria were assigned by a random number table to two groups, 31 in the treatment group and 32 in the drug control group. The treatment group received SGIP acupuncture therapy; while the control group was treated orally with pinaverium bromide. The treatment duration of both groups was 28 days. The clinical efficacy was evaluated and compared by scoring patient's symptom and QOL.
A significant difference was found by variance analysis in efficacies between the two groups (P<0.01), shown as the quicker initiation of effect (P<0.05) and the more evident clinical improvement in symptoms along the increase in treatment duration, as well as the more significant elevation of QOL in the acupuncture treatment group (P<0.01). SGIP displayed its superiority especially in improving dysphoria, conflict behavior, dietary restrictions, and social responses.
SGIP acupuncture treatment could effectively alleviate the degree and frequency of symptoms' attack in IBS-D patients, such as abdominal pain, diarrhea, abdominal distension, etc., markedly relieve the tenesmic sensation, with the efficacy better than that of pinaverium bromide, showing a preponderance in improving patient's QOL.
探讨和胃健脾针法（SGIP）针刺治疗对腹泻型肠易激综合征（IBS-D）患者临床症状及生活质量（QOL）的影响。
采用单盲随机对照研究，将符合纳入标准的 63 例患者按随机数字表法分为两组，治疗组 31 例，对照组 32 例。治疗组给予 SGIP 针刺治疗，对照组给予匹维溴铵口服治疗。两组疗程均为 28 天。通过评分比较患者的症状和 QOL 来评估和比较临床疗效。
两组疗效比较差异有统计学意义（P<0.01），表现为起效更快（P<0.05），症状随治疗时间的延长而改善更明显，针刺组 QOL 升高更明显（P<0.01）。SGIP 尤其在改善烦躁、冲突行为、饮食限制和社会反应方面具有优势。
SGIP 针刺治疗可有效缓解 IBS-D 患者腹痛、腹泻、腹胀等症状的严重程度和发作频率，明显缓解痉挛性疼痛，疗效优于匹维溴铵，在改善患者生活质量方面具有优势。
