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1
Sensitive and specific single-molecule sequencing of 5-hydroxymethylcytosine.
Nat Methods. 2011 Nov 20;9(1):75-7. doi: 10.1038/nmeth.1779.
2
Selective capture of 5-hydroxymethylcytosine from genomic DNA.
J Vis Exp. 2012 Oct 5(68):4441. doi: 10.3791/4441.
3
Bioorthogonal labeling of 5-hydroxymethylcytosine in genomic DNA and diazirine-based DNA photo-cross-linking probes.
Acc Chem Res. 2011 Sep 20;44(9):709-17. doi: 10.1021/ar2000502. Epub 2011 May 3.
4
High sensitivity 5-hydroxymethylcytosine detection in Balb/C brain tissue.
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5
Selective chemical labeling reveals the genome-wide distribution of 5-hydroxymethylcytosine.
Nat Biotechnol. 2011 Jan;29(1):68-72. doi: 10.1038/nbt.1732. Epub 2010 Dec 12.
6
Detection of 5-hydroxymethylcytosine in a combined glycosylation restriction analysis (CGRA) using restriction enzyme Taq(α)I.
Bioorg Med Chem Lett. 2011 Sep 1;21(17):5075-7. doi: 10.1016/j.bmcl.2011.03.118. Epub 2011 Apr 9.
7
Tet-assisted bisulfite sequencing of 5-hydroxymethylcytosine.
Nat Protoc. 2012 Dec;7(12):2159-70. doi: 10.1038/nprot.2012.137. Epub 2012 Nov 29.
8
Sensitive enzymatic quantification of 5-hydroxymethylcytosine in genomic DNA.
Nucleic Acids Res. 2010 Oct;38(19):e181. doi: 10.1093/nar/gkq684. Epub 2010 Aug 4.
9
Pull-down of 5-hydroxymethylcytosine DNA using JBP1-coated magnetic beads.
Nat Protoc. 2012 Jan 26;7(2):340-50. doi: 10.1038/nprot.2011.443.

引用本文的文献

2
Orthologous mammalian A3A-mediated single-nucleotide resolution sequencing of DNA epigenetic modification 5-hydroxymethylcytosine.
Chem Sci. 2025 Jan 28;16(9):3953-3963. doi: 10.1039/d4sc08660k. eCollection 2025 Feb 26.
5
Whole-Genome Sequencing of 5-Hydroxymethylcytosine at Base Resolution by Bisulfite-Free Single-Step Deamination with Engineered Cytosine Deaminase.
ACS Cent Sci. 2023 Nov 30;9(12):2315-2325. doi: 10.1021/acscentsci.3c01131. eCollection 2023 Dec 27.
6
Factors and Methods for the Detection of Gene Expression Regulation.
Biomolecules. 2023 Feb 6;13(2):304. doi: 10.3390/biom13020304.
8
Navigating the pitfalls of mapping DNA and RNA modifications.
Nat Rev Genet. 2023 Jun;24(6):363-381. doi: 10.1038/s41576-022-00559-5. Epub 2023 Jan 18.
10
Chemoenzymatic labeling of DNA methylation patterns for single-molecule epigenetic mapping.
Nucleic Acids Res. 2022 Sep 9;50(16):e92. doi: 10.1093/nar/gkac460.

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DNA demethylation dynamics.
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5-Hydroxymethylcytosine, the sixth base of the genome.
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Genome-wide mapping of 5-hydroxymethylcytosine in embryonic stem cells.
Nature. 2011 May 19;473(7347):394-7. doi: 10.1038/nature10102. Epub 2011 May 8.
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Genome-wide regulation of 5hmC, 5mC, and gene expression by Tet1 hydroxylase in mouse embryonic stem cells.
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TET1 and hydroxymethylcytosine in transcription and DNA methylation fidelity.
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Dynamic regulation of 5-hydroxymethylcytosine in mouse ES cells and during differentiation.
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Selective chemical labeling reveals the genome-wide distribution of 5-hydroxymethylcytosine.
Nat Biotechnol. 2011 Jan;29(1):68-72. doi: 10.1038/nbt.1732. Epub 2010 Dec 12.
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Real-time DNA sequencing from single polymerase molecules.
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