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百里香精油对多重耐药临床细菌菌株的抗菌活性。

The antimicrobial activity of thyme essential oil against multidrug resistant clinical bacterial strains.

机构信息

Medical and Sanitary Microbiology Department, Medical University of Lodz, Medical University of Lodz, Lodz, Poland.

出版信息

Microb Drug Resist. 2012 Apr;18(2):137-48. doi: 10.1089/mdr.2011.0080. Epub 2011 Nov 21.

DOI:10.1089/mdr.2011.0080
PMID:22103288
Abstract

AIM

The aim of this work was to investigate the antimicrobial activity of thyme essential oil against clinical multidrug resistant strains of Staphylococcus, Enterococcus, Escherichia, and Pseudomonas genus.

MATERIALS

The antibacterial activity of oil was tested against standard strains of bacteria and 120 clinical strains isolated from patients with infections of the oral cavity, abdominal cavity, respiratory and genitourinary tracts, skin, and from the hospital environment.

METHODS

Agar diffusion was used to determine the microbial growth inhibition of bacterial growth at various concentrations of oil from Thymus vulgaris. Susceptibility testing to antibiotics was carried out using disk diffusion.

RESULTS

Thyme essential oil strongly inhibited the growth of the clinical strains of bacteria tested.

CONCLUSIONS

The use of phytopharmaceuticals based on an investigated essential oil from thyme in the prevention and treatment of various human infections may be reasonable.

摘要

目的

本研究旨在探究百里香精油对临床多种耐药的葡萄球菌、肠球菌、大肠杆菌和假单胞菌属的抗菌活性。

材料

本研究采用琼脂扩散法,在百里香精油的不同浓度下,检测其对口腔、腹腔、呼吸道和泌尿道、皮肤感染患者及医院环境中分离的 120 株临床分离株和标准菌株的抑菌活性。药敏试验采用纸片扩散法。

结果

百里香精油强烈抑制所测试的临床分离株细菌的生长。

结论

基于百里香精油的植物药物在预防和治疗各种人类感染方面可能是合理的。

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