Royal Hospital for Women, Barker St, Randwick NSW 2031 Australia.
Eur J Oncol Nurs. 2012 Dec;16(5):453-9. doi: 10.1016/j.ejon.2011.10.007. Epub 2011 Nov 21.
To describe the quality of life, nutritional status and physical activity of women with gynaecological cancer over three time points.
Women referred to a major gynaecological cancer service in Sydney for initial treatment were invited to complete validated questionnaires at baseline, three and six months after diagnosis. Quality of life was assessed using the 36-item Short Form Health Survey (SF36) and the Symptom Distress Scale. Nutritional status was assessed using the Patient Generated-Subjective Global Assessment and physical activity was assessed using the International Physical Activity Questionnaire short form. Effect sizes corrected for correlation were calculated using Cohen's d and Friedman's test was used to compare scores. Complete case analysis was used.
Forty women were recruited and twenty-three (58%) completed assessment measures for all three time points. No important clinical or demographic differences existed between women who completed all measures and those who did not. Over the duration of the study, the number of well-nourished women increased from 16 to 21, while the number of malnourished women decreased from 7 to 2. Improvements in SF36 scores were seen in all aspects except general health, which declined (p>0.05). Statistically significant (p<0.05) improvements were seen for role physical, vitality, social functioning and role emotional. The median number of minutes of physical activity per week was highest at diagnosis and declined after that.
This study indicates the importance of assessing nutritional status at diagnosis for women with gynaecological cancer.
描述妇科癌症女性在三个时间点的生活质量、营养状况和身体活动情况。
邀请在悉尼接受初始治疗的妇科癌症患者参加该研究，要求她们在基线、诊断后 3 个月和 6 个月时填写经过验证的问卷。使用 36 项简短健康调查问卷（SF36）和症状困扰量表评估生活质量。使用患者自评主观整体评估评估营养状况，使用国际体力活动问卷短表评估身体活动。使用 Cohen's d 校正相关后计算效应大小，并使用 Friedman 检验比较分数。采用完整病例分析。
共招募了 40 名女性，其中 23 名（58%）完成了所有三个时间点的评估。完成所有评估的女性与未完成的女性在重要的临床或人口统计学方面没有差异。在研究期间，营养良好的女性人数从 16 人增加到 21 人，而营养不良的女性人数从 7 人减少到 2 人。SF36 评分在除总体健康状况外的所有方面均有所改善，而总体健康状况下降（p>0.05）。身体角色、活力、社会功能和情绪角色方面的评分均有显著改善（p<0.05）。每周身体活动的中位数分钟数在诊断时最高，此后逐渐下降。
本研究表明，在诊断时评估妇科癌症女性的营养状况非常重要。
