Rheinische Friedrich-Wilhelms-Universität Bonn, Kekulé-Institut für Organische Chemie und Biochemie, Gerhard-Domagk-Strasse 1, 53121 Bonn, Germany.
Chemistry. 2011 Dec 9;17(50):14164-9. doi: 10.1002/chem.201102182. Epub 2011 Nov 23.
The direct and selective phenol coupling reaction that provides biphenols still represents a challenge in organic synthesis. The recently developed electrosynthesis on boron-doped diamond anodes with fluorinated additives was developed further to allow the application to less-expensive electrodes and fluorinated media. This advanced protocol allows the highly selective anodic phenol coupling reaction on graphite with a broad scope.
直接且选择性的酚偶联反应为生成联苯提供了一种途径，但在有机合成中仍具有挑战性。最近开发的带有氟化添加剂的硼掺杂金刚石阳极电合成技术进一步得到了发展，使其能够应用于成本更低的电极和氟化介质。该先进的方案允许在石墨上进行高度选择性的阳极酚偶联反应，具有广泛的适用范围。
