Stafford Giles H, Bunn Jonathan R, Villar Richard N
The Richard Villar Practice, Spire Cambridge Lea Hospital, Cambridge, UK.
Hip Int. 2011 Nov-Dec;21(6):744-50. doi: 10.5301/HIP.2011.8843.
We describe one- to three-year results of a novel use of fibrin glue in the treatment of cartilage damage by arthroscopy in the hip. This technique uses the microfracture technique and fibrin adhesive to bond delaminated articular cartilage to the underlying subchondral bone. This is generally performed in conjunction with treatment of underlying pathology such as femoroacetabular impingement. Patients were assessed using the modified Harris Hip Score (MHHS) pre- and post-operatively, and statistical significance determined by Student's t-test. We report the mid-term results of 43 patients with femoroacetabular impingement who have undergone this technique for re-attachment of delaminated chondral flaps. There was a statistically significant improvement in MHHS at a mean of 28 months (16 to 42 months) after surgery (p<0.0001). The MHHS for pain improved significantly from 21.8 (95% CI 19.0 to 24.7) pre-operatively to 35.8 (95% CI 32.6 to 38.9) post-operatively (p<0.0001). The MHHS for function also showed significant, although more modest, improvements from 40.0 (95% CI 37.7 to 42.3) pre-operatively to 43.6 (95% CI 41.4 to 45.8) post-operatively (p=0.0006). There were three patients who had early (within 12 months of the index procedure) revision arthroscopy for iliopsoas pathology. Arthroscopic repair of delaminated acetabular articular cartilage using fibrin adhesive is a useful technique in the treatment of early cartilage damage. We have seen encouraging mid-term results, although further studies are warranted.
我们描述了一种新型纤维蛋白胶在髋关节镜治疗软骨损伤中的一至三年疗效。该技术采用微骨折技术和纤维蛋白粘合剂,将分层的关节软骨与下方的软骨下骨粘合。这通常与治疗潜在病变(如股骨髋臼撞击症)同时进行。术前和术后使用改良Harris髋关节评分(MHHS)对患者进行评估,并通过学生t检验确定统计学意义。我们报告了43例接受该技术修复分层软骨瓣重新附着的股骨髋臼撞击症患者的中期结果。术后平均28个月(16至42个月),MHHS有统计学显著改善(p<0.0001)。疼痛的MHHS从术前的21.8(95%CI 19.0至24.7)显著改善至术后的35.8(95%CI 32.6至38.9)(p<0.0001)。功能的MHHS也有显著改善,尽管改善程度较小,从术前的40.0(95%CI 37.7至42.3)提高至术后的43.6(95%CI 41.4至45.8)(p=0.0006)。有3例患者因髂腰肌病变在初次手术后12个月内进行了早期翻修关节镜检查。使用纤维蛋白粘合剂对分层髋臼关节软骨进行关节镜修复是治疗早期软骨损伤的一种有用技术。我们看到了令人鼓舞的中期结果,尽管仍需进一步研究。