Department of Oral Medicine and Radiology, MM College of Dental Sciences and Research, Ambala, Haryana, India.
Gerodontology. 2012 Jun;29(2):125-9. doi: 10.1111/j.1741-2358.2011.00580.x. Epub 2011 Nov 24.
The aim of this study was to verify the association between salivary calcium and serum oestrogen levels with oral dryness in post-menopausal women. Also, the correlation between these variables was evaluated.
A case-control study was carried out on 60 selected menopausal women with and without oral dryness feeling (30 as case and 30 as control) conducted in the Department of Oral Medicine and Radiology, Maharishi Markandeshar University, Mullana, India. Paraffin-stimulated saliva samples were obtained by expectoration. Salivary calcium concentrations were assessed colorimetrically using Arsenazo III reaction. The serum oestrogen concentration was measured using ELISA. Statistical analysis of Student's t-test and Pearson correlation was used.
There was significant difference in mean values of both salivary calcium concentration and serum oestrogen between case and control groups. The result obtained also showed that an inverse correlation was found between salivary calcium concentration and serum oestrogen levels in both the groups and in total sample size.
Oral dryness in post-menopausal women is associated with high levels of salivary calcium and low levels of serum oestrogen. The concentrations of salivary calcium and serum oestrogen are inversely correlated in post-menopausal women, regardless of the presence or absence of oral dryness.
本研究旨在验证唾液钙和血清雌激素水平与绝经后妇女口干之间的关联，并评估这些变量之间的相关性。
在印度马哈里希马克苏德大学穆拉纳分校口腔医学和放射科进行了一项病例对照研究，共纳入 60 名有或没有口干感觉的绝经后妇女（30 名病例和 30 名对照）。通过咳痰获得石蜡刺激唾液样本。使用 Arsenazo III 反应比色法评估唾液钙浓度。使用 ELISA 测量血清雌激素浓度。使用学生 t 检验和 Pearson 相关性进行统计分析。
病例组和对照组的唾液钙浓度和血清雌激素水平的平均值均存在显著差异。结果还表明，两组和总样本量中唾液钙浓度与血清雌激素水平之间存在负相关。
绝经后妇女的口干与唾液钙水平升高和血清雌激素水平降低有关。无论是否存在口干，绝经后妇女的唾液钙和血清雌激素浓度均呈负相关。
