Tehran University of Medical Sciences, Tehran, Iran.
Climacteric. 2012 Oct;15(5):496-9. doi: 10.3109/13697137.2011.624212. Epub 2011 Dec 20.
The aim of this study was to investigate serum, stimulated and unstimulated salivary magnesium in postmenopausal women with xerostomia.
A case-control study was carried out on 60 selected postmenopausal women aged 41-77 years with or without xerostomia (30 as cases with xerostomia and 30 as controls without xerostomia), conducted at the Clinic of Oral Medicine, Tehran University of Medical Sciences. Unstimulated and paraffin-stimulated saliva samples were obtained by expectoration. Magnesium concentration was determined by the spectrophotometer method. Statistical analysis was carried out using Student's t-test.
The mean serum concentration, but not stimulated and unstimulated whole saliva magnesium concentrations, was significantly higher in the cases than in the controls.
Serum magnesium level appears to be associated with xerostomia in menopause.
本研究旨在探讨口干症绝经后妇女血清、刺激和非刺激唾液中的镁含量。
在德黑兰医科大学口腔医学诊所进行了一项病例对照研究，共纳入 60 名年龄在 41-77 岁之间的绝经后妇女，根据是否有口干症（30 例口干症患者为病例组，30 例无口干症患者为对照组）进行分组。采用咳痰法获取未刺激和石蜡刺激唾液样本。采用分光光度计法测定镁浓度。采用 Student's t 检验进行统计学分析。
病例组的血清镁浓度均值高于对照组，但刺激和非刺激全唾液镁浓度无显著差异。
血清镁水平似乎与绝经后口干症有关。
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