Goette D K
Department of Medicine, Letterman Army Medical Center, Presidio of San Francisco, CA 94129-6700.
J Am Acad Dermatol. 1990 Aug;23(2 Pt 1):257-62. doi: 10.1016/0190-9622(90)70209-z.
Unfamiliarity of physicians with chilblains (perniosis) gives rise to unnecessary hospital admissions with expensive laboratory and radiologic evaluations and, at times, hazardous therapy. Seven cases of chilblains were seen in San Francisco from November 1986 through January 1987. The patients presented with pruritic, at times painful, purple acral patches or plaques on the fingers, toes, and nose after exposure to a cool or a cold, damp environment. Histologic examination in two cases revealed a perivascular lymphocytic infiltrate with endothelial swelling of the subcutaneous fat and of the upper and lower dermal plexus.
医生对冻疮(冻伤)不熟悉,导致不必要的住院治疗,进行昂贵的实验室和放射学检查,有时还采用危险的治疗方法。1986年11月至1987年1月期间,在旧金山共诊治了7例冻疮患者。这些患者在暴露于凉爽、寒冷、潮湿的环境后,手指、脚趾和鼻子上出现瘙痒、有时疼痛的紫色肢端斑块或斑片。两例患者的组织学检查显示,皮下脂肪以及真皮上下丛血管周围有淋巴细胞浸润,内皮细胞肿胀。