Institute for Ophthalmic Research, Centre for Ophthalmology, University of Tübingen, Tübingen, Germany.
Ophthalmic Res. 2012;47(4):171-88. doi: 10.1159/000329603. Epub 2011 Nov 26.
The objective of this work was to study the epidemiology of major eye diseases leading to blindness in Europe through a systematic literature review. The literature search was performed using the Medline database (PubMed), with MeSH and free text search terms. Inclusion criteria for the studies were: (a) performed on a healthy population of Caucasian origin aged between 50 and 75 years; (b) diagnosed by ophthalmological examination in accordance with the International Classification of Diseases 10; (c) contained a detailed description of the sampling and diagnostic procedures and data resources; (d) sample size>500, and (e) published between 1990 and 2008. The results of 57 studies on the prevalence and incidence of age-related macular degeneration, diabetic retinopathy and glaucoma are reported, providing an up-to-date and comprehensive overview of these diseases in Europe from an epidemiological perspective.
本研究旨在通过系统文献回顾来研究导致欧洲人群失明的主要眼病的流行病学。文献检索使用 Medline 数据库（PubMed），采用 MeSH 和自由文本检索词。研究的纳入标准为：（a）在年龄在 50 至 75 岁之间的白种人健康人群中进行；（b）根据国际疾病分类第 10 版进行眼科检查诊断；（c）包含详细的抽样和诊断程序以及数据资源描述；（d）样本量>500，（e）发表于 1990 年至 2008 年期间。报告了 57 项关于年龄相关性黄斑变性、糖尿病视网膜病变和青光眼的患病率和发病率的研究结果，从流行病学角度提供了欧洲这些疾病的最新和全面概述。
