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体外抗菌和抗真菌活性的漆大姑用于治疗腹泻在突尼斯民间医学。

In vitro antibacterial and antifungal activities of Rhus tripartitum used as antidiarrhoeal in Tunisian folk medicine.

机构信息

Laboratoire de Biochimie, Faculté de Médecine de Sousse, 4002 Sousse, Tunisia.

出版信息

Nat Prod Res. 2012;26(23):2215-8. doi: 10.1080/14786419.2011.639072. Epub 2011 Dec 2.

DOI:10.1080/14786419.2011.639072
PMID:22132736
Abstract

Rhus tripartitum (African sumac) is a plant commonly used in Tunisian traditional medicine to treat diarrhoea and dysentery. In this study, we have demonstrated that R. tripartitum extracts exhibited a significant broad spectrum activity against one or more of the test microorganisms with a zone size ranging from 8 to 28 mm in diameter. These diameters are much higher than those obtained with standard antibiotics. The chloroformic extracts were found to be effective against bacterial and fungal strains tested, with MIC values ranging between 0.07 and 0.62 mg mL(-1) against Staphylococcus aureus and Candida albicans. However, ethyl-acetate/methanol fractions showed a selective activity only against bacterial microorganisms with low MIC values between 0.07 and 0.15 mg mL(-1). The overall results suggested that the traditional use of R. tripartitum for the treatment of diarrhoea tract infections was attributed to the presence of antibacterial agents.

摘要

三叶漆(非洲漆木)是一种常用于突尼斯传统医学治疗腹泻和痢疾的植物。在这项研究中,我们已经证明,三叶漆提取物对一种或多种测试微生物具有显著的广谱活性,其直径范围为 8 至 28 毫米。这些直径远高于标准抗生素的直径。氯仿提取物对测试的细菌和真菌菌株有效,对金黄色葡萄球菌和白色念珠菌的 MIC 值在 0.07 至 0.62 mg/mL 之间。然而,乙酸乙酯/甲醇馏分仅对细菌微生物具有选择性活性,MIC 值在 0.07 至 0.15 mg/mL 之间。总的结果表明,传统上使用三叶漆治疗腹泻感染是由于存在抗菌剂。

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