Department of Chemistry, University of Chicago, 5735 South Ellis Avenue, Chicago, Illinois 60637, USA.
J Am Chem Soc. 2012 Jan 11;134(1):111-4. doi: 10.1021/ja2095393. Epub 2011 Dec 9.
A general method for regioselective C3-benzylation of indoles has been developed. Various 3-substituted indoles and benzyl methyl carbonates with different electronic properties react under mild conditions to afford a diverse range of 3-benzylindolenine products in good yields.
一种吲哚 C3 位区域选择性苄基化的通用方法已经开发出来。各种具有不同电子性质的 3-取代吲哚和苄基碳酸甲酯在温和条件下反应,以良好的收率得到了一系列不同的 3-苄基吲哚啉产物。