Bevelacqua Resources, 343 Adair Drive, Richland, WA 99352, USA.
Health Phys. 2012 Jan;102(1):2-7. doi: 10.1097/HP.0b013e318227e80d.
The angular dependence of the absorbed dose from internal radiation-generating devices located within a tumor mass is investigated. Given the systematics of proton and heavy-ion differential scattering cross sections, candidate internal radiation-generating devices will have a relatively constant absorbed dose output beyond a critical angle. Inside this angle, the absorbed dose output is suppressed because elastic and inelastic differential cross sections are peaked in the beam direction. This peaking increases in severity as the particle energy increases and suggests internal radiation-generating devices must have a limited rotation capability to compensate for the depression in the absorbed dose for angles near the beam direction.
研究了位于肿瘤内的内部辐射发生装置的吸收剂量的角度依赖性。考虑到质子和重离子微分散射截面的系统学，候选内部辐射发生装置在临界角之外将具有相对恒定的吸收剂量输出。在这个角度内，由于弹性和非弹性微分截面在射束方向上呈峰值，吸收剂量输出受到抑制。随着粒子能量的增加，这种峰值变得更加严重，这表明内部辐射发生装置必须具有有限的旋转能力，以补偿靠近射束方向的角度处吸收剂量的下降。
