Department of Immunology and Pathogen Biology, Xi'an Jiaotong University College of Medicine, China.
J Zhejiang Univ Sci B. 2011 Dec;12(12):998-1007. doi: 10.1631/jzus.B1100079.
To identify sociodemographic characteristics and risk factor of Demodex infestation, 756 students aged 13-22 years in Xi'an, China were sampled for the school-based cross-sectional study. Demodex was examined using the cellophane tape method (CTP). The results showed that the total detection rate of Demodex was 67.6%. Logistic regression analysis revealed that five variables (gender, residence, sharing sanitary ware, frequency of face-wash per day, and use of facial cleanser) were found to be uncorrelated with Demodex infestation, whereas three variables (age, skin type, and skin disease) were found to be independent correlates. Students aged over 18 years had 22.1 times higher odds of Demodex infestation compared to those under 16 years and students aged 16-18 years also had 2.1 times higher odds compared to those aged 13-15 years. Odds of having a Demodex infestation for oily or mixed skin were 2.1 times those for dry or neutral skin. Students with a facial skin disease had 3.0 times higher odds of being infested with Demodex compared to those without. The inception rate of students with facial dermatoses increased in parallel with increasing mite count. The inception rates were 21.3%, 40.7%, 59.2%, and 67.7% in the negative, mild, moderate, and severe infestation groups, respectively (χ(2)=60.6, P<0.001). Specifically, the amount of infested mites and inception rate of acne vulgaris were positively correlated (R(2)=0.57, moderate infestation odds ratio (OR)=7.1, severe infestation OR=10.3). It was concluded that Demodex prevalence increases with age, and Demodex presents in nearly all adult human. Sebaceous hyperplasia with oily or mixed skin seems to favour Demodex proliferation. Demodex infestation could be associated with acne vulgaris. The CTP is a good sampling method for studies of Demodex prevalence.
为了确定蠕形螨感染的社会人口统计学特征和危险因素，在中国西安，对 756 名年龄在 13-22 岁的学生进行了基于学校的横断面研究。采用透明胶带法（CTP）检查蠕形螨。结果显示，总检出率为 67.6%。Logistic 回归分析显示，5 个变量（性别、居住地、共用卫生洁具、每天洗脸频率和使用洗面奶）与蠕形螨感染无关，而 3 个变量（年龄、皮肤类型和皮肤病）是独立的相关因素。18 岁以上的学生感染蠕形螨的几率是 16 岁以下学生的 22.1 倍，16-18 岁的学生感染蠕形螨的几率是 13-15 岁学生的 2.1 倍。油性或混合性皮肤感染蠕形螨的几率是干性或中性皮肤的 2.1 倍。患有面部皮肤病的学生感染蠕形螨的几率是无面部皮肤病学生的 3.0 倍。随着螨虫计数的增加，患有面部皮肤病的学生的发病（感染）率呈平行增加。在阴性、轻度、中度和重度感染组中，发病率分别为 21.3%、40.7%、59.2%和 67.7%（χ(2)=60.6，P<0.001）。具体来说，感染螨虫的数量和寻常痤疮的发病（感染）率呈正相关（R(2)=0.57，中度感染的优势比（OR）=7.1，重度感染 OR=10.3）。结论是，蠕形螨的患病率随年龄增长而增加，几乎所有成年人都有蠕形螨。皮脂分泌过多的油性或混合性皮肤似乎有利于蠕形螨的增殖。蠕形螨感染可能与寻常痤疮有关。CTP 是一种研究蠕形螨流行率的良好采样方法。
