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腹腔镜胃囊和残胃切除术:一种治疗Roux-en-Y胃旁路术后难治性吻合口溃疡的新方法:病例报告

Laparoscopic gastric pouch and remnant resection: a novel approach to refractory anastomotic ulcers after Roux-en-Y gastric bypass: case report.

作者信息

Steinemann Daniel C, Schiesser Marc, Clavien Pierre-Alain, Nocito Antonio

机构信息

Department of Visceral and Transplantation Surgery, University Hospital Zurich, Raemistrasse 100, 8091 Zurich, Switzerland.

出版信息

BMC Surg. 2011 Dec 2;11:33. doi: 10.1186/1471-2482-11-33.

Abstract

BACKGROUND

Anastomotic or marginal ulcers occur in 0.6 to 16% of patients after laparoscopic Roux-en-Y-Gastric Bypass. Initial therapy aims at eliminating known risk factors including smoking, Helicobacter pylori infection, use of non-steroidal anti-inflammatory drugs and inhibition of gastric acid secretion. While this approach is successful in 68 to 88% of the cases, up to one third of patients need a subsequent surgical revision. However, marginal ulcers still recur in up to 10% of cases after revisional surgery, thus constituting a serious challenge for bariatric surgeons.

CASE PRESENTATION

We herein report a case of an insidious marginal ulcer refractory to both medical therapy with high-dosed proton pump inhibitors and sucralfate as well as surgical therapy consisting of the lengthening of a short alimentary limb and later resection of the gastroenterostomy and construction of a new tension-free anastomosis. Only after gastrectomy by laparoscopic en-bloc resection of the gastrojejunostomy, the gastric pouch and resection of the gastric remnant with reconstruction by esophagojejunostomy the patient remained free of symptoms.

CONCLUSION

By laparoscopic resection of the entire gastric pouch and the gastric remnant the risk to leave a suboptimally vascularised or even ischemic pouch in situ was avoided. The esophagojejunostomy was then created in healthy, good vascularised tissue. In our case this novel approach was effective in the management of a refractory anastomotic ulcer and might represent a rescue option when simple revision of the gastrojejunostomy fails.

摘要

背景

腹腔镜Roux-en-Y胃旁路术后,吻合口或边缘性溃疡在0.6%至16%的患者中出现。初始治疗旨在消除已知的危险因素,包括吸烟、幽门螺杆菌感染、使用非甾体抗炎药以及抑制胃酸分泌。虽然这种方法在68%至88%的病例中取得成功,但高达三分之一的患者需要后续的手术修正。然而,在修正手术后,边缘性溃疡仍有高达10%的病例复发,因此对减肥外科医生构成了严峻挑战。

病例报告

我们在此报告一例隐匿性边缘性溃疡病例,该溃疡对高剂量质子泵抑制剂和硫糖铝的药物治疗以及包括延长短消化道肢体、随后切除胃肠吻合口并构建新的无张力吻合术的手术治疗均无效。仅在通过腹腔镜整块切除胃空肠吻合口、胃袋并切除胃残余部分并通过食管空肠吻合术重建后,患者才无症状。

结论

通过腹腔镜切除整个胃袋和胃残余部分,避免了将血管化不佳甚至缺血的胃袋留在原位的风险。然后在健康、血管化良好的组织中创建食管空肠吻合术。在我们的病例中,这种新方法在治疗难治性吻合口溃疡方面有效,并且在简单的胃空肠吻合术修正失败时可能是一种挽救选择。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/809f/3247190/ebcb95d3d0e2/1471-2482-11-33-1.jpg

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