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《国家共病调查复制版青少年补充调查中 DSM-IV 障碍的患病率、持续时间及社会人口学相关因素》

Prevalence, persistence, and sociodemographic correlates of DSM-IV disorders in the National Comorbidity Survey Replication Adolescent Supplement.

作者信息

Kessler Ronald C, Avenevoli Shelli, Costello E Jane, Georgiades Katholiki, Green Jennifer Greif, Gruber Michael J, He Jian-ping, Koretz Doreen, McLaughlin Katie A, Petukhova Maria, Sampson Nancy A, Zaslavsky Alan M, Merikangas Kathleen Ries

机构信息

Department of Health Care Policy, Harvard Medical School, Boston, MA 02115, USA.

出版信息

Arch Gen Psychiatry. 2012 Apr;69(4):372-80. doi: 10.1001/archgenpsychiatry.2011.160. Epub 2011 Dec 5.

Abstract

CONTEXT

Community epidemiological data on the prevalence and correlates of adolescent mental disorders are needed for policy planning purposes. Only limited data of this sort are available.

OBJECTIVE

To present estimates of 12-month and 30-day prevalence, persistence (12-month prevalence among lifetime cases and 30-day prevalence among 12-month cases), and sociodemographic correlates of commonly occurring DSM-IV disorders among adolescents in the National Comorbidity Survey Replication Adolescent Supplement.

DESIGN

The National Comorbidity Survey Replication Adolescent Supplement is a US national survey of DSM-IV anxiety, mood, behavior, and substance disorders among US adolescents based on face-to-face interviews in the homes of respondents with supplemental parent questionnaires.

SETTING

Dual-frame household and school samples of US adolescents.

PARTICIPANTS

A total of 10,148 adolescents aged 13 to 17 years (interviews) and 1 parent of each adolescent (questionnaires).

MAIN OUTCOME MEASURES

The DSM-IV disorders assessed with the World Health Organization Composite International Diagnostic Interview and validated with blinded clinical interviews based on the Schedule for Affective Disorders and Schizophrenia for School-Age Children. Good concordance (area under the receiver operating characteristic curve ≥0.80) was found between Composite International Diagnostic Interview and Schedule for Affective Disorders and Schizophrenia for School-Age Children diagnoses.

RESULTS

The prevalence estimates of any DSM-IV disorder are 40.3% at 12 months (79.5% of lifetime cases) and 23.4% at 30 days (57.9% of 12-month cases). Anxiety disorders are the most common class of disorders, followed by behavior, mood, and substance disorders. Although relative disorder prevalence is quite stable over time, 30-day to 12-month prevalence ratios are higher for anxiety and behavior disorders than mood or substance disorders, suggesting that the former are more chronic than the latter. The 30-day to 12-month prevalence ratios are generally lower than the 12-month to lifetime ratios, suggesting that disorder persistence is due more to episode recurrence than to chronicity. Sociodemographic correlates are largely consistent with previous studies.

CONCLUSIONS

Among US adolescents, DSM-IV disorders are highly prevalent and persistent. Persistence is higher for adolescents than among adults and appears to be due more to recurrence than chronicity of child-adolescent onset disorders.

摘要

背景

为了政策规划,需要有关青少年精神障碍患病率及其相关因素的社区流行病学数据。但此类数据有限。

目的

在全国共病调查复制青少年补充调查中,呈现青少年常见的DSM-IV障碍的12个月和30天患病率估计值、持续性(终生病例中的12个月患病率以及12个月病例中的30天患病率)以及社会人口学相关因素。

设计

全国共病调查复制青少年补充调查是一项针对美国青少年的DSM-IV焦虑、情绪、行为和物质使用障碍的全国性调查,基于在受访者家中进行的面对面访谈以及补充的家长问卷。

设置

美国青少年的双框架家庭和学校样本。

参与者

共有10148名13至17岁的青少年(接受访谈)以及每名青少年的1名家长(填写问卷)。

主要结局指标

使用世界卫生组织综合国际诊断访谈评估DSM-IV障碍,并根据学龄儿童情感障碍和精神分裂症日程表通过盲法临床访谈进行验证。综合国际诊断访谈与学龄儿童情感障碍和精神分裂症日程表诊断之间发现了良好的一致性(受试者工作特征曲线下面积≥0.80)。

结果

任何DSM-IV障碍的患病率估计值在12个月时为40.3%(终生病例的79.5%),在30天时为23.4%(12个月病例的57.9%)。焦虑障碍是最常见的障碍类型,其次是行为、情绪和物质使用障碍。尽管相对障碍患病率随时间相当稳定,但焦虑和行为障碍的30天至12个月患病率比值高于情绪或物质使用障碍,表明前者比后者更具慢性。30天至12个月患病率比值通常低于12个月至终生患病率比值,表明障碍的持续性更多是由于发作复发而非慢性病程。社会人口学相关因素在很大程度上与先前研究一致。

结论

在美国青少年中,DSM-IV障碍高度流行且具有持续性。青少年的持续性高于成年人,似乎更多是由于儿童青少年期起病障碍的复发而非慢性病程。

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