Division of Gastroenterology and Hepatology, Department of Internal Medicine, Keio University School of Medicine, Tokyo, Japan.
J Neurogastroenterol Motil. 2011 Oct;17(4):360-5. doi: 10.5056/jnm.2011.17.4.360. Epub 2011 Oct 31.
Among functional gastrointestinal (GI) disorders, functional dyspepsia (FD) and irritable bowel syndrome (IBS) are important to public health around the world and are frequently encountered in general practice. Upper GI symptoms such as heartburn, postprandial fullness, early satiety, epigastric pain or burning and lower GI symptoms such as constipation and diarrhea often coexist. Although the prevalence of FD-IBS overlap would be influenced by the selection of the study population, the overlap rate of FD-IBS could be in the range of 11%-27%. Specifically, FD-IBS overlap is associated with more severe symptoms than FD alone or IBS alone. Since clinical overlap, especially FD-IBS overlap, is very common, the 2 syndromes should not be treated in a mutually exclusive fashion.
在功能性胃肠（GI）疾病中，功能性消化不良（FD）和肠易激综合征（IBS）对全球公共卫生很重要，并且在普通实践中经常遇到。上 GI 症状，如烧心、餐后饱胀、早饱、上腹痛或烧灼感，以及下 GI 症状，如便秘和腹泻，经常同时存在。尽管 FD-IBS 重叠的患病率会受到研究人群选择的影响，但 FD-IBS 的重叠率可能在 11%-27%之间。具体来说，FD-IBS 重叠与比 FD 或 IBS 单独存在更严重的症状相关。由于临床重叠，特别是 FD-IBS 重叠很常见，因此不应以相互排斥的方式对待这两种综合征。
