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埃及裂谷热病毒和疫苗观察。

Observations on rift valley fever virus and vaccines in Egypt.

机构信息

Virology department, Animal Health Research Institute, Dokki, Giza, Egypt.

出版信息

Virol J. 2011 Dec 12;8:532. doi: 10.1186/1743-422X-8-532.

Abstract

Rift Valley Fever virus (RVFV, genus: Phlebovirus, family: Bunyaviridae), is an arbovirus which causes significant morbidity and mortality in animals and humans. RVFV was introduced for the first time in Egypt in 1977. In endemic areas, the insect vector control and vaccination is considering appropriate measures if applied properly and the used vaccine is completely safe and the vaccination programs cover all the susceptible animals. Egypt is importing livestock and camels from the African Horn & the Sudan for human consumption. The imported livestock and camels were usually not vaccinated against RVFV. But in rare occasions, the imported livestock were vaccinated but with unknown date of vaccination and the unvaccinated control contacts were unavailable for laboratory investigations. Also, large number of the imported livestock and camels are often escaped slaughtering for breeding which led to the spread of new strains of FMD and the introduction of RVFV from the enzootic African countries. This article provide general picture about the present situation of RVFV in Egypt to help in controlling this important disease.

摘要

裂谷热病毒(RVFV,属:白蛉病毒科,科:布尼亚病毒科)是一种虫媒病毒,可导致动物和人类出现严重的发病率和死亡率。1977 年,该病毒首次在埃及被发现。在流行地区,如果昆虫媒介控制和疫苗接种措施应用得当,所用疫苗完全安全,接种计划涵盖所有易感动物,则可以考虑采取这些措施。埃及从非洲之角和苏丹进口牲畜和骆驼供人类食用。进口的牲畜和骆驼通常没有接种 RVFV 疫苗。但在极少数情况下,进口的牲畜接种了疫苗,但不知道接种日期,且无法获得未接种的对照接触者进行实验室调查。此外,大量进口的牲畜和骆驼经常逃避屠宰用于繁殖,这导致了新的口蹄疫菌株的传播,并从流行的非洲国家引入了 RVFV。本文提供了埃及 RVFV 现状的概述,以帮助控制这种重要疾病。

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