Department of Pathology, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA.
Adv Anat Pathol. 2012 Jan;19(1):1-10. doi: 10.1097/PAP.0b013e318234ab36.
Distinction between endometrioid and serous carcinomas of the endometrium has important prognostic and therapeutic implications. Misdiagnosing a serous carcinoma as endometrioid can have significant consequences for the patient and pathologist. Although many cases are straightforward and easy to classify, there are occasional problematic cases. This review focuses on strategies that help differentiate between low-grade endometrioid carcinoma and serous carcinoma of the endometrium. We will discuss clinical, morphologic, and immunohistochemical differences between the 2 entities and provide practical tips for practicing pathologists when confronted with this differential diagnosis.
子宫内膜的子宫内膜样癌和浆液性癌之间的区别具有重要的预后和治疗意义。将浆液性癌误诊为子宫内膜样癌可能会对患者和病理学家产生重大影响。尽管许多病例是明确的且易于分类，但偶尔也会有棘手的病例。本综述重点讨论有助于区分低级别子宫内膜样癌和子宫内膜浆液性癌的策略。我们将讨论这两种实体之间的临床、形态和免疫组织化学差异，并为遇到这种鉴别诊断的病理学家提供实用技巧。
