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近期吸入性皮质类固醇与生长的相关研究。

Recent research on inhaled corticosteroids and growth.

机构信息

Division of Endocrinology and Diabetes, The Children's Hospital of Philadelphia, Perelman School of Medicine at the University of Pennsylvania, USA.

出版信息

Curr Opin Endocrinol Diabetes Obes. 2012 Feb;19(1):53-6. doi: 10.1097/MED.0b013e32834edab5.

DOI:10.1097/MED.0b013e32834edab5
PMID:22157405
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7478236/
Abstract

PURPOSE OF REVIEW

Description of recent studies evaluating growth and inhaled corticosteroids.

RECENT FINDINGS

Corticosteroids are the gold standard of asthma maintenance treatment, but effects on growth remain controversial. This is a review of recent research in this area, which has focused on medications causing less adrenal suppression as well as alternative regimens for chronic illness such as asthma.

SUMMARY

The use of newer corticosteroids and regimens shows short-term evidence of minimal growth effects without worsening of asthma control.

摘要

目的综述

描述最近评估生长和吸入皮质类固醇的研究。

最近的发现

皮质类固醇是哮喘维持治疗的金标准,但对生长的影响仍存在争议。这是对该领域最近研究的综述,重点是引起较少肾上腺抑制作用的药物以及哮喘等慢性疾病的替代方案。

摘要

使用较新的皮质类固醇和方案显示出短期对生长影响最小的证据,同时不会使哮喘控制恶化。

相似文献

1
Recent research on inhaled corticosteroids and growth.近期吸入性皮质类固醇与生长的相关研究。
Curr Opin Endocrinol Diabetes Obes. 2012 Feb;19(1):53-6. doi: 10.1097/MED.0b013e32834edab5.
2
Clinical safety of inhaled corticosteroids for asthma in children: an update of long-term trials.儿童哮喘吸入性糖皮质激素的临床安全性:长期试验的最新情况
Drug Saf. 2006;29(7):599-612. doi: 10.2165/00002018-200629070-00005.
3
[Inhalation corticosteroids and the growth of asthmatic children].[吸入性糖皮质激素与哮喘儿童的生长发育]
Ned Tijdschr Geneeskd. 1999 Dec 11;143(50):2546-7.
4
[Inhalation corticosteroids and the growth of asthmatic children].[吸入性糖皮质激素与哮喘儿童的生长发育]
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Addressing steroid phobia: improving the risk-benefit ratio with new agents.应对类固醇恐惧症:使用新型药物改善风险效益比。
Allergy Asthma Proc. 2008 Jul-Aug;29(4):358-64. doi: 10.2500/aap.2008.29.3132.
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[No risk of development of osteoporosis or inhibition of growth in children with asthma treated with inhaled corticosteroids].[吸入性糖皮质激素治疗的哮喘儿童无骨质疏松症发生风险或生长抑制]
Ugeskr Laeger. 2005 Jun 6;167(23):2502-3.
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The impact of asthma and its treatment on growth: an evidence-based review.哮喘及其治疗对生长的影响:基于证据的综述。
J Pediatr (Rio J). 2019 Mar-Apr;95 Suppl 1:10-22. doi: 10.1016/j.jped.2018.10.005. Epub 2018 Nov 22.
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Potential adverse endocrine effects of inhaled corticosteroids.吸入性糖皮质激素潜在的内分泌不良反应。
J Paediatr Child Health. 1996 Aug;32(4):278-80. doi: 10.1111/j.1440-1754.1996.tb02552.x.
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Inhaled corticosteroids and growth in children.吸入性糖皮质激素与儿童生长发育
Pediatr Ann. 1998 Nov;27(11):752-8. doi: 10.3928/0090-4481-19981101-11.
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[Inhalation corticosteroids and the growth of asthmatic children].[吸入性糖皮质激素与哮喘儿童的生长发育]
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Treatment of mild persistent asthma in children.儿童轻度持续性哮喘的治疗。
Lancet. 2011 May 21;377(9779):1743; author reply 1744. doi: 10.1016/S0140-6736(11)60723-X.
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Use of beclomethasone dipropionate as rescue treatment for children with mild persistent asthma (TREXA): a randomised, double-blind, placebo-controlled trial.丙酸倍氯米松作为轻度持续性哮喘儿童(TREXA)抢救治疗的应用:一项随机、双盲、安慰剂对照试验。
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Efficacy and safety of three ciclesonide doses vs placebo in children with asthma: the RAINBOW study.三种环索奈德剂量与安慰剂在哮喘儿童中的疗效和安全性:RAINBOW 研究。
Respir Med. 2010 Nov;104(11):1618-28. doi: 10.1016/j.rmed.2010.06.012. Epub 2010 Jul 8.
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New asthma drugs: small molecule inhaled corticosteroids.新型哮喘药物:小分子吸入性皮质类固醇。
Curr Opin Pharmacol. 2010 Jun;10(3):260-5. doi: 10.1016/j.coph.2010.06.001. Epub 2010 Jun 17.
6
Lower-leg growth rates in children with asthma during treatment with ciclesonide and fluticasone propionate.哮喘患儿在接受西替利嗪和丙酸氟替卡松治疗期间的小腿生长速度。
Pediatr Allergy Immunol. 2010 Feb;21(1 Pt 2):e199-205. doi: 10.1111/j.1399-3038.2009.00879.x. Epub 2009 Mar 23.
7
A randomized trial of lower leg and height growth in children with asthma treated with inhaled budesonide from a new dry powder inhaler.一项随机试验研究了使用新型干粉吸入器吸入布地奈德治疗哮喘的儿童下肢和身高增长情况。
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Childhood asthma practice guideline part three: update of the 2007 National Guidelines for the Diagnosis and Treatment of Asthma. The National Asthma Education and Prevention Program.儿童哮喘实践指南第三部分:2007年《国家哮喘诊断与治疗指南》更新版。国家哮喘教育与预防计划。
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Effects of inhaled steroids on growth, bone metabolism, and adrenal function.吸入性类固醇对生长、骨代谢及肾上腺功能的影响。
Adv Pediatr. 2006;53:101-10. doi: 10.1016/j.yapd.2006.04.006.
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Update of growth effects of inhaled and intranasal corticosteroids.吸入性和鼻内用糖皮质激素生长效应的最新进展。
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