近期吸入性皮质类固醇与生长的相关研究。
Recent research on inhaled corticosteroids and growth.
机构信息
Division of Endocrinology and Diabetes, The Children's Hospital of Philadelphia, Perelman School of Medicine at the University of Pennsylvania, USA.
出版信息
Curr Opin Endocrinol Diabetes Obes. 2012 Feb;19(1):53-6. doi: 10.1097/MED.0b013e32834edab5.
Abstract
PURPOSE OF REVIEW
Description of recent studies evaluating growth and inhaled corticosteroids.
RECENT FINDINGS
Corticosteroids are the gold standard of asthma maintenance treatment, but effects on growth remain controversial. This is a review of recent research in this area, which has focused on medications causing less adrenal suppression as well as alternative regimens for chronic illness such as asthma.
SUMMARY
The use of newer corticosteroids and regimens shows short-term evidence of minimal growth effects without worsening of asthma control.
摘要
目的综述
描述最近评估生长和吸入皮质类固醇的研究。
最近的发现
皮质类固醇是哮喘维持治疗的金标准，但对生长的影响仍存在争议。这是对该领域最近研究的综述，重点是引起较少肾上腺抑制作用的药物以及哮喘等慢性疾病的替代方案。
摘要
使用较新的皮质类固醇和方案显示出短期对生长影响最小的证据，同时不会使哮喘控制恶化。
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本文引用的文献
1
Treatment of mild persistent asthma in children.儿童轻度持续性哮喘的治疗。
Lancet. 2011 May 21;377(9779):1743; author reply 1744. doi: 10.1016/S0140-6736(11)60723-X.
2
Use of beclomethasone dipropionate as rescue treatment for children with mild persistent asthma (TREXA): a randomised, double-blind, placebo-controlled trial.丙酸倍氯米松作为轻度持续性哮喘儿童（TREXA）抢救治疗的应用：一项随机、双盲、安慰剂对照试验。
Lancet. 2011 Feb 19;377(9766):650-7. doi: 10.1016/S0140-6736(10)62145-9. Epub 2011 Feb 14.
3
Combination therapy salmeterol/fluticasone versus doubling dose of fluticasone in children with asthma.沙美特罗/氟替卡松联合治疗与加倍剂量氟替卡松治疗哮喘儿童的比较。
Am J Respir Crit Care Med. 2010 Nov 15;182(10):1221-7. doi: 10.1164/rccm.201002-0193OC. Epub 2010 Jul 9.
4
Efficacy and safety of three ciclesonide doses vs placebo in children with asthma: the RAINBOW study.三种环索奈德剂量与安慰剂在哮喘儿童中的疗效和安全性：RAINBOW 研究。
Respir Med. 2010 Nov;104(11):1618-28. doi: 10.1016/j.rmed.2010.06.012. Epub 2010 Jul 8.
5
New asthma drugs: small molecule inhaled corticosteroids.新型哮喘药物：小分子吸入性皮质类固醇。
Curr Opin Pharmacol. 2010 Jun;10(3):260-5. doi: 10.1016/j.coph.2010.06.001. Epub 2010 Jun 17.
6
Lower-leg growth rates in children with asthma during treatment with ciclesonide and fluticasone propionate.哮喘患儿在接受西替利嗪和丙酸氟替卡松治疗期间的小腿生长速度。
Pediatr Allergy Immunol. 2010 Feb;21(1 Pt 2):e199-205. doi: 10.1111/j.1399-3038.2009.00879.x. Epub 2009 Mar 23.
7
A randomized trial of lower leg and height growth in children with asthma treated with inhaled budesonide from a new dry powder inhaler.一项随机试验研究了使用新型干粉吸入器吸入布地奈德治疗哮喘的儿童下肢和身高增长情况。
Pediatr Allergy Immunol. 2010 Feb;21(1 Pt 2):e206-12. doi: 10.1111/j.1399-3038.2009.00875.x. Epub 2009 Mar 3.
8
Childhood asthma practice guideline part three: update of the 2007 National Guidelines for the Diagnosis and Treatment of Asthma. The National Asthma Education and Prevention Program.儿童哮喘实践指南第三部分：2007年《国家哮喘诊断与治疗指南》更新版。国家哮喘教育与预防计划。
J Pediatr Health Care. 2009 Jan-Feb;23(1):59-61. doi: 10.1016/j.pedhc.2008.10.004.
9
Effects of inhaled steroids on growth, bone metabolism, and adrenal function.吸入性类固醇对生长、骨代谢及肾上腺功能的影响。
Adv Pediatr. 2006;53:101-10. doi: 10.1016/j.yapd.2006.04.006.
10
Update of growth effects of inhaled and intranasal corticosteroids.吸入性和鼻内用糖皮质激素生长效应的最新进展。
Curr Opin Allergy Clin Immunol. 2002 Feb;2(1):7-10. doi: 10.1097/00130832-200202000-00002.
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