Fertility and IVF Unit, Department of Obstetrics and Gynecology, Carmel Medical Center, the Bruce Rappaport Faculty of Medicine, Technion, Haifa, Israel.
Asian J Androl. 2012 Jan;14(1):69-76. doi: 10.1038/aja.2011.69. Epub 2011 Dec 12.
Women have been increasingly delaying the start of motherhood in recent decades. The same trend is seen also for men. The influence of maternal age on fertility, chromosomal anomalies, pregnancy complications, and impaired perinatal and post-natal outcome of offspring, has been thoroughly investigated, and these aspects are clinically applied during fertility and pregestational counseling. Male aging and reproductive outcome has gained relatively less attention. The purpose of this review is to evaluate updated and relevant literature on the effect of paternal age on reproductive outcome.
近年来,女性越来越晚地开始生育。这种趋势同样也出现在男性身上。母亲年龄对生育能力、染色体异常、妊娠并发症以及后代围产期和产后结局的影响已经得到了深入研究,这些方面在生育和孕前咨询中得到了临床应用。男性衰老和生殖结局相对较少受到关注。本文旨在评估关于父亲年龄对生殖结局影响的最新相关文献。