Occupational and Environmental Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, Maryland 20892, USA.
Mol Carcinog. 2012 Jan;51(1):98-108. doi: 10.1002/mc.20779.
Several occupational exposures have been linked to excess risk of pancreatic cancer; however, most associations are not well established. The objective of this review article is to report on the more recently published studies (1998-2010), and provide a summary of the most consistently reported occupational risk factors for pancreatic cancer, including exposure to chlorinated hydrocarbon compounds, pesticides, polycyclic aromatic hydrocarbons (PAHs), metals, nitrosamines, radiation, various airborne particles, and employment in sedentary occupations. We conclude that the strongest and most consistent findings linking occupational exposures with pancreatic cancer risk to date are for chlorinated hydrocarbons and PAHs.
一些职业暴露已被证实与胰腺癌风险增加相关；然而，大多数关联尚未得到很好的确立。本文的目的是报告最近发表的研究（1998-2010 年），并总结最一致报道的胰腺癌职业危险因素，包括接触氯化碳氢化合物、农药、多环芳烃（PAHs）、金属、亚硝胺、辐射、各种空气传播颗粒以及久坐职业。我们的结论是，迄今为止，将职业暴露与胰腺癌风险联系起来的最强和最一致的发现是与氯化碳氢化合物和 PAHs 有关。
